Ranjan Vivek Kumar, Saha Tilak, Mukherjee Shriparna, Chakraborty Ranadhir
OMICS Laboratory, Department of Biotechnology, University of North Bengal, Siliguri, West Bengal, India.
Microbiology and Immunology Laboratory, Department of Zoology, University of North Bengal, Siliguri, West Bengal, India.
Genome Announc. 2018 Jan 18;6(3):e01443-17. doi: 10.1128/genomeA.01443-17.
The draft genome sequence of a novel strain, sp. MR 02, a pyomelanin-producing bacterium isolated from the Mahananda River at Siliguri, West Bengal, India, is reported here. This strain has a genome size of 5.94 Mb, with an overall G+C content of 62.6%. The draft genome reports 5,799 genes (mean gene length, 923 bp), among which 5,503 are protein-coding genes, including the genes required for the catabolism of tyrosine or phenylalanine for the characteristic production of homogentisic acid (HGA). Excess HGA, on excretion, auto-oxidizes and polymerizes to form pyomelanin.
本文报道了从印度西孟加拉邦西里古里的马哈南达河分离出的一种新型菌株——产脓性黑色素细菌MR 02菌株的基因组序列草图。该菌株的基因组大小为5.94 Mb，总体G+C含量为62.6%。基因组草图报告了5799个基因（平均基因长度为923 bp），其中5503个是蛋白质编码基因，包括酪氨酸或苯丙氨酸分解代谢所需的基因，用于特征性地产生尿黑酸（HGA）。过量的HGA排泄后会自动氧化并聚合形成脓性黑色素。
