• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

解析小儿慢性疼痛中的睡眠-疼痛关系:内化心理健康症状的中介作用。

Disentangling the Sleep-Pain Relationship in Pediatric Chronic Pain: The Mediating Role of Internalizing Mental Health Symptoms.

作者信息

Pavlova Maria, Ference Jennifer, Hancock Megan, Noel Melanie

机构信息

Department of Psychology, University of Calgary, Calgary, AB, Canada.

Alberta Children's Hospital, Calgary, AB, Canada.

出版信息

Pain Res Manag. 2017;2017:1586921. doi: 10.1155/2017/1586921. Epub 2017 Nov 16.

DOI:10.1155/2017/1586921
PMID:29348713
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5733870/
Abstract

BACKGROUND

Pediatric chronic pain often emerges in adolescence and cooccurs with internalizing mental health issues and sleep impairments. Emerging evidence suggests that sleep problems may precede the onset of chronic pain as well as anxiety and depression. Studies conducted in pediatric populations with pain-related chronic illnesses suggest that internalizing mental health symptoms may mediate the sleep-pain relationship; however, this has not been examined in youth with primary pain disorders.

OBJECTIVE

To examine whether anxiety and depressive symptoms mediated relationships between sleep quality and pain outcomes among youth with chronic pain.

METHODS

Participants included 147 youth (66.7% female) aged 8-18 years who were referred to a tertiary-level chronic pain program. At intake, the youth completed psychometrically sound measures of sleep quality, pain intensity, pain interference, and anxiety and depressive symptoms.

RESULTS

As hypothesized, poor sleep quality was associated with increased pain intensity and pain interference, and anxiety and depressive symptoms mediated these sleep-pain relationships.

DISCUSSION

For youth with chronic pain, poor sleep quality may worsen pain through alterations in mood and anxiety; however, prospective research using objective measures is needed. Future research should examine whether targeting sleep and internalizing mental health symptoms in treatments improve pain outcomes in these youth.

摘要

背景

儿童慢性疼痛通常在青春期出现,并与内化性心理健康问题和睡眠障碍同时发生。新出现的证据表明,睡眠问题可能先于慢性疼痛以及焦虑和抑郁的发作。在患有与疼痛相关的慢性疾病的儿科人群中进行的研究表明,内化性心理健康症状可能介导睡眠与疼痛的关系;然而,这在患有原发性疼痛障碍的青少年中尚未得到研究。

目的

研究焦虑和抑郁症状是否介导慢性疼痛青少年的睡眠质量与疼痛结果之间的关系。

方法

参与者包括147名年龄在8至18岁之间的青少年(66.7%为女性),他们被转诊至三级慢性疼痛项目。在入院时,这些青少年完成了关于睡眠质量、疼痛强度、疼痛干扰以及焦虑和抑郁症状的心理测量学可靠的测量。

结果

如假设的那样,睡眠质量差与疼痛强度增加和疼痛干扰增加有关,并且焦虑和抑郁症状介导了这些睡眠与疼痛的关系。

讨论

对于患有慢性疼痛的青少年,睡眠质量差可能通过情绪和焦虑的改变而加重疼痛;然而,需要使用客观测量方法进行前瞻性研究。未来的研究应该检查在治疗中针对睡眠和内化性心理健康症状是否能改善这些青少年的疼痛结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/933e/5733870/12d03d85fea8/PRM2017-1586921.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/933e/5733870/12d03d85fea8/PRM2017-1586921.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/933e/5733870/12d03d85fea8/PRM2017-1586921.001.jpg

相似文献

1
Disentangling the Sleep-Pain Relationship in Pediatric Chronic Pain: The Mediating Role of Internalizing Mental Health Symptoms.解析小儿慢性疼痛中的睡眠-疼痛关系:内化心理健康症状的中介作用。
Pain Res Manag. 2017;2017:1586921. doi: 10.1155/2017/1586921. Epub 2017 Nov 16.
2
Sleep Mediates the Association Between PTSD Symptoms and Chronic Pain in Youth.睡眠介导 PTSD 症状与青少年慢性疼痛之间的关联。
J Pain. 2018 Jan;19(1):67-75. doi: 10.1016/j.jpain.2017.09.002. Epub 2017 Sep 27.
3
Finding Silver Linings: A Preliminary Examination of Benefit Finding in Youth With Chronic Pain.寻找一线希望:慢性疼痛青少年的益处发现初探。
J Pediatr Psychol. 2018 Apr 1;43(3):285-293. doi: 10.1093/jpepsy/jsx126.
4
The role of fatigue in functional outcomes for youth with chronic pain.疲劳在慢性疼痛青少年功能结局中的作用。
Eur J Pain. 2019 Sep;23(8):1548-1562. doi: 10.1002/ejp.1431. Epub 2019 Jul 1.
5
The role of sleep problems in the development of depression in those with persistent pain: a prospective cohort study.睡眠问题在持续性疼痛人群中发展为抑郁的作用:一项前瞻性队列研究。
Sleep. 2013 Nov 1;36(11):1693-8. doi: 10.5665/sleep.3130.
6
Sleep Quality Among People Living With Chronic Noncancer Pain: Findings From the Pain and Opioids IN Treatment (POINT) Cohort.慢性非癌性疼痛患者的睡眠质量:疼痛与阿片类药物治疗(POINT)队列研究结果
Clin J Pain. 2016 May;32(5):380-7. doi: 10.1097/AJP.0000000000000282.
7
Predicting Multiple Facets of School Functioning in Pediatric Chronic Pain: Examining the Direct Impact of Anxiety.预测小儿慢性疼痛中学校功能的多个方面:探究焦虑的直接影响。
Clin J Pain. 2015 Oct;31(10):867-75. doi: 10.1097/AJP.0000000000000181.
8
Psychiatric disorders and association with quality of sleep and quality of life in patients with chronic pain: a SCID-based study.精神障碍与慢性疼痛患者睡眠质量和生活质量的关系:基于 SCID 的研究。
Pain Med. 2014 May;15(5):772-81. doi: 10.1111/pme.12390. Epub 2014 Feb 25.
9
Fatigue, sleep-wake pattern, depressive and anxiety symptoms and body-mass index: analysis in a sample of episodic and chronic migraine patients.疲劳、睡眠-觉醒模式、抑郁和焦虑症状以及体重指数:发作性和慢性偏头痛患者样本分析
Neurol Sci. 2016 Jun;37(6):987-9. doi: 10.1007/s10072-016-2505-1. Epub 2016 Feb 15.
10
Impact of Sleep Disturbance on Fatigue, Nausea, and Pain: Mediating Role of Depressive Symptoms Among Youth With Disorders of Gut-Brain Interaction.睡眠障碍对疲劳、恶心和疼痛的影响:肠道-脑交互障碍青少年中抑郁症状的中介作用。
J Pediatr Gastroenterol Nutr. 2023 Oct 1;77(4):468-473. doi: 10.1097/MPG.0000000000003887. Epub 2023 Sep 20.

引用本文的文献

1
"Hurt and Misunderstood": Emotional reactions to pain dismissal in emerging adults with chronic pain.“受伤与误解”:慢性疼痛的新兴成年人对疼痛忽视的情绪反应
Health Care Transit. 2025 Aug 4;3:100116. doi: 10.1016/j.hctj.2025.100116. eCollection 2025.
2
Changes in sleep patterns in primary care workers during the first wave of the COVID-19 pandemic in 2022 in Shanghai: a cross-sectional study.2022 年上海 COVID-19 大流行第一波期间初级保健工作者睡眠模式的变化:一项横断面研究。
Sci Rep. 2024 May 29;14(1):12373. doi: 10.1038/s41598-024-61311-z.
3
Exploring Referral and Service Utilization Patterns Within an Outpatient Interdisciplinary Pediatric Chronic Pain Program.

本文引用的文献

1
Sleep Quality, Affect, Pain, and Disability in Children With Chronic Pain: Is Affect a Mediator or Moderator?慢性疼痛儿童的睡眠质量、情感、疼痛与残疾:情感是中介变量还是调节变量?
J Pain. 2017 Sep;18(9):1087-1095. doi: 10.1016/j.jpain.2017.04.007. Epub 2017 May 4.
2
Longitudinal and Temporal Associations Between Daily Pain and Sleep Patterns After Major Pediatric Surgery.小儿大手术后每日疼痛与睡眠模式的纵向及时间关联
J Pain. 2017 Jun;18(6):656-663. doi: 10.1016/j.jpain.2017.01.004. Epub 2017 Jan 26.
3
Use of Smartphones to Prospectively Evaluate Predictors and Outcomes of Caregiver Responses to Pain in Youth with Chronic Disease.
探索门诊跨学科儿科慢性疼痛项目中的转诊和服务利用模式。
J Pain Res. 2024 Feb 3;17:525-533. doi: 10.2147/JPR.S430411. eCollection 2024.
4
Prevention is better than cure: why early interventions for insomnia and chronic pain during adolescence should be a priority.预防胜于治疗:为何青少年失眠和慢性疼痛的早期干预应成为优先事项。
Front Psychol. 2023 Jun 8;14:1206977. doi: 10.3389/fpsyg.2023.1206977. eCollection 2023.
5
Healthcare Professionals' Knowledge about Pediatric Chronic Pain: A Systematic Review.医疗保健专业人员对儿童慢性疼痛的认知:一项系统综述
Children (Basel). 2023 Mar 31;10(4):665. doi: 10.3390/children10040665.
6
The complexities of the sleep-pain relationship in adolescents: A critical review.青少年睡眠与疼痛关系的复杂性:批判性综述。
Sleep Med Rev. 2023 Feb;67:101715. doi: 10.1016/j.smrv.2022.101715. Epub 2022 Nov 12.
7
Pain, depressive symptoms, and health-related quality of life among survivors of pediatric hematopoietic stem cell transplant.儿科造血干细胞移植幸存者的疼痛、抑郁症状和健康相关生活质量。
Pediatr Blood Cancer. 2022 Oct;69(10):e29846. doi: 10.1002/pbc.29846. Epub 2022 Jun 23.
8
Pediatric sleep and pain: etiologies, consequences, and clinical considerations.儿科睡眠与疼痛:病因、后果及临床相关问题。
J Clin Sleep Med. 2022 Sep 1;18(9):2281-2289. doi: 10.5664/jcsm.10008.
9
A Pilot Study Investigating the Role of Gender in the Intergenerational Relationships between Gene Expression, Chronic Pain, and Adverse Childhood Experiences in a Clinical Sample of Youth with Chronic Pain.一项探索性别在慢性疼痛青少年临床样本中基因表达、慢性疼痛和不良童年经历的代际关系中所起作用的试点研究。
Epigenomes. 2021 Apr 15;5(2):9. doi: 10.3390/epigenomes5020009.
10
Autistic Traits and Attention-Deficit Hyperactivity Disorder Symptoms Associated With Greater Pain Interference and Depression, and Reduced Health-Related Quality of Life in Children With Chronic Pain.自闭症特质与注意力缺陷多动障碍症状与慢性疼痛儿童的更强疼痛干扰、抑郁相关,且与健康相关生活质量降低有关。
Front Neurosci. 2021 Nov 1;15:716887. doi: 10.3389/fnins.2021.716887. eCollection 2021.
使用智能手机前瞻性评估慢性病青少年疼痛护理中照顾者反应的预测因素和结果。
Pain. 2017 Apr;158(4):629-636. doi: 10.1097/j.pain.0000000000000804. Epub 2016 Dec 15.
4
A Single Arm Pilot Trial of Brief Cognitive Behavioral Therapy for Insomnia in Adolescents with Physical and Psychiatric Comorbidities.针对患有躯体和精神共病的青少年失眠症的简短认知行为疗法单臂试点试验。
J Clin Sleep Med. 2017 Mar 15;13(3):401-410. doi: 10.5664/jcsm.6490.
5
Mental Health Comorbidities in Pediatric Chronic Pain: A Narrative Review of Epidemiology, Models, Neurobiological Mechanisms and Treatment.儿童慢性疼痛中的心理健康共病:流行病学、模型、神经生物学机制及治疗的叙述性综述
Children (Basel). 2016 Dec 2;3(4):40. doi: 10.3390/children3040040.
6
Child and Family Antecedents of Pain During the Transition to Adolescence: A Longitudinal Population-Based Study.青少年过渡期疼痛的儿童及家庭影响因素:一项基于人群的纵向研究。
J Pain. 2016 Nov;17(11):1174-1182. doi: 10.1016/j.jpain.2016.07.005. Epub 2016 Aug 4.
7
Self-Reported Time in Bed and Sleep Quality in Association with Internalizing and Externalizing Symptoms in School-Age Youth.自我报告的学龄青少年卧床时间和睡眠质量与内化和外化症状的关系。
Child Psychiatry Hum Dev. 2017 Jun;48(3):455-467. doi: 10.1007/s10578-016-0672-1.
8
Post-traumatic stress symptoms in children and adolescents with chronic pain: A topical review of the literature and a proposed framework for future research.慢性疼痛儿童和青少年的创伤后应激症状:文献综述及未来研究的框架建议
Eur J Pain. 2016 Oct;20(9):1371-83. doi: 10.1002/ejp.879. Epub 2016 Jun 8.
9
Anxiety Adversely Impacts Response to Cognitive Behavioral Therapy in Children with Chronic Pain.焦虑对慢性疼痛儿童认知行为疗法的反应产生不利影响。
J Pediatr. 2016 Apr;171:227-33. doi: 10.1016/j.jpeds.2016.01.018. Epub 2016 Feb 12.
10
Sleep problems and pain: a longitudinal cohort study in emerging adults.睡眠问题与疼痛:一项针对青年期个体的纵向队列研究。
Pain. 2016 Apr;157(4):957-963. doi: 10.1097/j.pain.0000000000000466.