Chahla Jorge, Kennedy Nicholas I, Geeslin Andrew G, Moatshe Gilbert, Cinque Mark E, DePhillipo Nicholas N, LaPrade Robert F
Steadman Philippon Research Institute, Vail, Colorado, U.S.A.
The Steadman Clinic, Vail, Colorado, U.S.A.
Arthrosc Tech. 2017 Nov 6;6(6):e2065-e2069. doi: 10.1016/j.eats.2017.08.006. eCollection 2017 Dec.
Meniscal injuries and meniscal loss are associated with changes in knee kinematics and loading, ultimately leading to poor functional outcomes and increased risk of progression to osteoarthritis. Biomechanical studies have shown restored knee function, and clinical studies have reported improved outcomes and decreased risk of osteoarthritis after meniscal repair. This has led orthopaedic surgeons to try and save the meniscus by repair whenever possible, as shown by increasing incidence of meniscal repair surgeries. Historically, meniscal lesions, particularly those greater in size and located in the white-white region of the meniscus, have been shown to have poor healing. In recent years, there has been an increasing interest in the use of biologic agents to help stimulate and expedite healing in traditionally more avascular tissue. Preliminary results for biologic therapeutic agents, such as platelet rich plasma and bone marrow aspirate concentrate, have been encouraging. However, these options are more demanding in regard to time, financial burden, resources, and regulations than some more classic agents such as fibrin clots. Fibrin clot is readily available, easy to use, affordable, and minimally invasive. This Technical Note describes a step-by-step and reproducible technique for harvesting, preparation, and using a fibrin clot to augment healing of meniscal repairs.
半月板损伤和半月板缺失与膝关节运动学及负荷的改变相关,最终导致功能预后不良以及发展为骨关节炎的风险增加。生物力学研究表明膝关节功能得以恢复,临床研究也报道了半月板修复后预后改善且骨关节炎风险降低。这使得骨科医生尽可能尝试通过修复来保留半月板,半月板修复手术的发生率增加就表明了这一点。从历史上看,半月板损伤,尤其是那些尺寸较大且位于半月板白区的损伤,愈合情况较差。近年来,人们越来越关注使用生物制剂来帮助刺激和加速传统上血供较差组织的愈合。生物治疗剂,如富血小板血浆和骨髓抽吸浓缩物的初步结果令人鼓舞。然而,与一些更传统的制剂(如纤维蛋白凝块)相比,这些选择在时间、经济负担、资源和监管方面要求更高。纤维蛋白凝块容易获得、使用方便、价格低廉且微创。本技术说明描述了一种用于采集、制备和使用纤维蛋白凝块以增强半月板修复愈合的分步且可重复的技术。