Chrysanthou Chrysanthos, Laliotis Nikolaos, Paraskevas George K, Anastasopoulos Nikolaos, Packer Gregory
Orthopaedics and Traumatology, Interbalkan Medical Center, Thessaloniki, GRC.
Anatomy and Surgical Anatomy, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Cureus. 2024 Jan 27;16(1):e53083. doi: 10.7759/cureus.53083. eCollection 2024 Jan.
This study conducted a comparative analysis of meniscal rupture repair, evaluating outcomes with and without the application of an exogenous fibrin clot to enhance meniscus repair. The research incorporated a relatively large sample size (24 patients) and employed a randomized control group with similar age characteristics and morphological types of meniscal ruptures as the study group. Notably, two postoperative follow-up times, at the third and 12th postoperative months, were utilized, distinguishing this study from related research. In the third postoperative month assessment, the fibrin clot technique demonstrated a significant advantage over simple stapling, as evidenced by markedly improved Tegner Lysholm Knee Scoring Scale (TLKSS) and Modified Cincinnati Rating System Questionnaire (MCRSQ) clinical assessment scores. Subsequent MRI scans at 12 months post-treatment revealed a high rate (91.67%) of complete healing in menisci treated with a fibrin clot, with only 4.17% exhibiting incomplete healing. This study expanded on previous research by including longitudinal ruptures and bucket-handle ruptures in addition to radial ruptures. The findings highlight a notable early improvement (third postoperative month) in the clinical assessment of longitudinal and bucket-handle ruptures treated with a fibrin clot during meniscus repair. This research contributes valuable insights into the efficacy of fibrin clots in enhancing meniscus repair, suggesting positive clinical and radiological outcomes, especially in the early stages postoperatively.
本研究对半月板破裂修复进行了比较分析,评估了应用外源性纤维蛋白凝块与未应用外源性纤维蛋白凝块增强半月板修复的效果。该研究纳入了相对较大的样本量(24例患者),并采用了年龄特征和半月板破裂形态类型与研究组相似的随机对照组。值得注意的是,本研究与相关研究的不同之处在于,术后利用了第三个月和第十二个月这两个随访时间点。在术后第三个月的评估中,纤维蛋白凝块技术相较于单纯缝合表现出显著优势,这在Tegner Lysholm膝关节评分量表(TLKSS)和改良辛辛那提评分系统问卷(MCRSQ)临床评估得分的显著提高中得到了证明。治疗后12个月的后续MRI扫描显示,接受纤维蛋白凝块治疗的半月板完全愈合率很高(91.67%),只有4.17%表现为不完全愈合。本研究在以往研究的基础上进行了扩展,除了放射状破裂外,还纳入了纵向破裂和桶柄状破裂。研究结果突出了在半月板修复过程中,接受纤维蛋白凝块治疗的纵向和桶柄状破裂在临床评估中的显著早期改善(术后第三个月)。这项研究为纤维蛋白凝块在增强半月板修复方面的疗效提供了有价值的见解,表明了积极的临床和放射学结果,尤其是在术后早期。