Cuarón A, Acero A, Cueto L
Arch Inst Cardiol Mex. 1985 Nov-Dec;55(6):535-46.
The natural history of pulmonary embolism is described, together with the physiopathologic alterations and the clinical manifestations of this disease, correlating these with the various patterns of pulmonary perfusion usually found by lung scintigraphy with 99mTc-MAA in patients with thromboembolic lung disease. By using data found in the literature, the operating characteristics (sensitivity, specificity, and accuracy) and the predictive values of the different scintigraphic patterns, were calculated for populations with different prevalences of pulmonary embolism. It is concluded that perfusion lung scintigraphy is a non-invasive, objective and fast procedure, very sensitive to alterations of the regional blood flow, but that is not specific for embolism. In some cases it can replace pulmonary angiography but in others, its results may indicate the performance of invasive procedures.
本文描述了肺栓塞的自然病史，以及该疾病的生理病理改变和临床表现，并将这些与血栓栓塞性肺病患者通过99mTc-MAA肺闪烁显像通常发现的各种肺灌注模式相关联。通过使用文献中的数据，针对不同肺栓塞患病率的人群计算了不同闪烁显像模式的操作特征（敏感性、特异性和准确性）以及预测值。得出的结论是，灌注肺闪烁显像是一种非侵入性、客观且快速的检查方法，对局部血流改变非常敏感，但对栓塞不具有特异性。在某些情况下，它可以替代肺血管造影，但在其他情况下，其结果可能提示需要进行侵入性检查。
