Department of Preventive Dentistry, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou, China.
Caries Res. 2018;52(3):230-245. doi: 10.1159/000484988. Epub 2018 Jan 20.
Research on the association between dental caries and body mass index (BMI) in children has shown contradictory results; thus we aimed to examine the association between dental caries and the full range of BMI classes among children. We comprehensively searched PubMed, Embase, and the Cochrane Library for studies published prior to March 2017. Articles comparing dental caries among the full range of BMI classes for children below 18 years of both genders were included. Fourteen studies were eligible for this study. Basic information - i.e., first author, published year, study design, country, sample size, age, type of dental caries index and BMI, main results and conclusions, and means and standard deviations of the dental caries indexes used - was pooled. The weighted mean differences and corresponding 95% confidence intervals for dental caries between children with abnormal weight and those with normal weight were analyzed. Generally, no significant differences in caries were found between any abnormal-weight group and the normal-weight group for both primary and permanent teeth. Sensitivity analyses showed that the obese group had more caries than the normal-weight group in their primary teeth. Significantly more caries was found among the overweight and obese children in both primary and permanent teeth in high-income countries, but not in low- and middle-income countries. We recommend that further studies use suitable sample sizes, unify the criteria for BMI categorization and the dental caries index, and investigate the confounding factors that might influence dental caries and BMI.
儿童龋齿与体重指数（BMI）相关性的研究结果相互矛盾，因此，本研究旨在探讨儿童各 BMI 类别与龋齿之间的相关性。我们全面检索了 PubMed、Embase 和 Cochrane 图书馆，纳入了截至 2017 年 3 月之前发表的所有研究。比较了 18 岁以下男女儿童各 BMI 类别龋齿情况的研究被纳入分析。共有 14 项研究符合纳入标准。提取的基本信息包括：第一作者、发表年份、研究设计、国家、样本量、年龄、龋齿指数和 BMI 类型、主要结果和结论，以及使用的龋齿指数的均数和标准差。采用加权均数差值及其 95%置信区间分析了异常体重儿童与正常体重儿童之间的龋齿差异。总体而言，对于乳牙和恒牙，异常体重组与正常体重组之间的龋齿无显著差异。敏感性分析显示，肥胖组儿童的乳牙龋齿较正常体重组更多。在高收入国家，超重和肥胖儿童的乳牙和恒牙龋齿均明显多于正常体重儿童，但在中低收入国家则不然。我们建议进一步的研究采用合适的样本量，统一 BMI 分类和龋齿指数的标准，并探讨可能影响龋齿和 BMI 的混杂因素。
