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[隔姜灸穴位联合方剂对卵巢储备功能下降患者的影响]

[Effects of ginger-separated moxibustion at points combined with formula on patients with decreased ovarian reserve function].

作者信息

Jiang Duosheng, Zhang Yingchun, Wu Xiaolan, Wang Yanming, Fan Qiangfang, Wu Song

机构信息

Department of TCM, Maternal and Child Health Hospital of Hubei Province, Wuhan 430070, China.

Department of Gynecology, Huanggang TCM Hospital.

出版信息

Zhongguo Zhen Jiu. 2017 Oct 12;37(10):1057-60. doi: 10.13703/j.0255-2930.2017.10.008.

DOI:10.13703/j.0255-2930.2017.10.008
PMID:29354973
Abstract

OBJECTIVE

To compare the efficacy differences between ginger-separated moxibustion at points combined with formula and formula alone on patients with decreased ovarian reserve function.

METHODS

Fifty patients of decreased ovarian reserve function were randomly divided into an observation group and a control group, 25 cases in each one. The patients in the observation group were treated with ginger-separated moxibustion at points combined with formula; the moxibustion was given for 1.5 h, once every seven days, and no treatment was given during menstrual period. The patients in the control group were treated with formula. One-month treatment was taken as one treatment course, and totally three courses were given. The change of follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E), anti-mullerian hormone (AMH), antral follicle count (AFC), peak systolic velocity (PSV), resistance index (RI) were observed before and after treatment in the two groups.

RESULTS

After treatment, the FSH, FSH/LH and RI were significantly lowered, but the E, AFC, PSV were significantly increased in the two groups (all <0.05); the FSH, FSH/LH and E in the observation group were lower and AFC was higher than those in the control group (all <0.05).

CONCLUSION

The ginger-separated moxibustion at points combined with formula are superior to formula alone in improving ovarian reserve function.

摘要

目的

比较穴位隔姜灸联合方剂与单纯方剂对卵巢储备功能下降患者的疗效差异。

方法

将50例卵巢储备功能下降患者随机分为观察组和对照组,每组25例。观察组采用穴位隔姜灸联合方剂治疗;艾灸1.5小时,每7天1次,经期不治疗。对照组采用单纯方剂治疗。以1个月治疗为1个疗程,共给予3个疗程。观察两组治疗前后卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E)、抗苗勒管激素(AMH)、窦卵泡计数(AFC)、收缩期峰值流速(PSV)、阻力指数(RI)的变化。

结果

治疗后,两组FSH、FSH/LH及RI均显著降低,E、AFC、PSV均显著升高(均P<0.05);观察组FSH、FSH/LH及E低于对照组,AFC高于对照组(均P<0.05)。

结论

穴位隔姜灸联合方剂在改善卵巢储备功能方面优于单纯方剂。

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