Department of Clinical Medicine - Universidade Federal Fluminense, Post Graduation Program in Medical Sciences from the Fluminense Federal University, Niterói, Brazil.
Department of Clinical Medicine - Universidade Federal Fluminense, Post Graduation Program in Cardiovascular Sciences from the Fluminense Federal University, Niterói, Brazil.
Geriatr Gerontol Int. 2018 May;18(5):732-737. doi: 10.1111/ggi.13241. Epub 2018 Jan 22.
Population aging is a worldwide phenomenon associated with physiological and metabolic changes that contribute to the increased prevalence of risk factors for cardiovascular disease. The phase angle (PA) is a variable calculated by bioelectrical impedance analysis, interpreted as a direct measure of cell stability. The objective of the present study was to investigate the correlation of PA with the anthropometric measures, metabolic profile and the cardiovascular risk estimated by the Global Cardiovascular Risk Score in the elderly population.
A cross-sectional study was carried out with 402 patients aged >60 years (70.4 ± 6.9 years, 74% female) treated in primary care. Patients were evaluated by blood pressure, anthropometric measurements and body composition. The score of the risk and the stratification of the cardiovascular risk were calculated using the criteria from the Framingham Heart Study.
Age, systolic blood pressure, neck circumference and fat-free mass correlated with PA in female patients. In men, age and systolic blood pressure were the variables that correlated with the PA in the bivariate analysis. In the multiple linear regression, for the female group the risk score presented an independent variation with PA (P = 0.051) and age (P < 0.0001). The same correlation was observed for the male group both for PA (P = 0.042) and age (P < 0.0001).
The present data show an independent association of PA with overall cardiovascular risk in the elderly population. Geriatr Gerontol Int 2018; 18: 732-737.
人口老龄化是一种全球现象，与生理和代谢变化有关，这些变化导致心血管疾病危险因素的患病率增加。相位角（PA）是生物电阻抗分析计算出的一个变量，被解释为细胞稳定性的直接衡量指标。本研究的目的是探讨 PA 与人体测量指标、代谢特征以及通过全球心血管风险评分估计的心血管风险在老年人群中的相关性。
这是一项横断面研究，共纳入了 402 名年龄在 60 岁以上（70.4±6.9 岁，74%为女性）的在基层医疗机构接受治疗的患者。患者接受血压、人体测量和身体成分评估。使用弗雷明汉心脏研究的标准计算风险评分和心血管风险分层。
女性患者的年龄、收缩压、颈围和去脂体重与 PA 相关。在男性中，年龄和收缩压是与 PA 相关的双变量分析中的变量。在多元线性回归中，对于女性组，风险评分与 PA （P=0.051）和年龄（P<0.0001）呈独立变化。对于男性组，PA （P=0.042）和年龄（P<0.0001）也观察到了相同的相关性。
本研究数据显示，PA 与老年人群的整体心血管风险独立相关。
