a Department of Psychiatry, Geisel School of Medicine and Centers for Health and Aging , Dartmouth College , Lebanon , NH , USA.
b Department of Rehabilitation and Health Services , University of North Texas , Denton , TX , USA.
Aging Ment Health. 2019 Apr;23(4):470-474. doi: 10.1080/13607863.2017.1423025. Epub 2018 Jan 22.
To examine pain-related activity interference as a mediator for the relationship between pain intensity and depressive symptoms among older adults with serious mental illness (SMI).
Ordinary least-squares regressions were used to investigate the mediation analysis among older adults with SMI (n = 183) from community mental health centers. Analyses used secondary data from the HOPES intervention study.
Higher pain intensity was associated with greater pain-related activity interference. Higher pain intensity and pain-related activity interference were also associated with elevated depressive symptoms. Finally, greater pain-related activity interference significantly mediated the association between higher pain intensity and elevated depressive symptoms.
These findings demonstrate that pain and depressive symptoms may be linked to functional limitations. Clinicians and researchers in the mental health field should better address pain-related activity interference among older adults with SMI, especially among those with higher pain intensity and elevated depressive symptoms.
探讨疼痛相关活动障碍在老年严重精神障碍（SMI）患者疼痛强度与抑郁症状之间的关系中的中介作用。
采用普通最小二乘法回归分析，对社区心理健康中心的老年 SMI 患者（n=183）进行中介分析。分析使用了 HOPES 干预研究的二级数据。
更高的疼痛强度与更大的疼痛相关活动障碍相关。更高的疼痛强度和疼痛相关活动障碍也与更高的抑郁症状相关。最后，更大的疼痛相关活动障碍显著中介了更高的疼痛强度与更高的抑郁症状之间的关联。
这些发现表明，疼痛和抑郁症状可能与功能障碍有关。精神卫生领域的临床医生和研究人员应更好地解决老年 SMI 患者的疼痛相关活动障碍，尤其是那些疼痛强度更高和抑郁症状更严重的患者。
