分析美国食品药品监督管理局批准的含硫原子药物。
Analysis of US FDA-Approved Drugs Containing Sulfur Atoms.
机构信息
Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, 85721, USA.
Department of Pharmacology and Toxicology, University of Arizona, Tucson, AZ, 85721, USA.
出版信息
Top Curr Chem (Cham). 2018 Jan 22;376(1):5. doi: 10.1007/s41061-018-0184-5.
In this review, we discuss all sulfur-containing FDA-approved drugs and their structures. The second section of the review is dedicated to structural analysis and is divided into 14 subsections, each focusing on one type of sulfur-containing moiety. A concise graphical representation of each class features drugs that are organized on the basis of structural similarity, evolutionary relevance, and medical indication. This review offers a unique and comprehensive overview of the structural features of all sulfur-containing FDA-approved drugs to date.
在这篇综述中，我们讨论了所有含硫的 FDA 批准药物及其结构。综述的第二部分专门进行结构分析，分为 14 个小节，每个小节都关注一种含硫基团。每个类别都有简洁的图形表示，其中包含根据结构相似性、进化相关性和医学适应症组织的药物。这篇综述提供了迄今为止所有含硫 FDA 批准药物的结构特征的独特而全面的概述。
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