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布地奈德治疗嗜酸性胆管炎

Eosinophilic cholangitis treatment with budesonide.

作者信息

De Roza Marianne Anastasia, Lim Chee Hooi

机构信息

Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore 169856, Singapore.

出版信息

World J Hepatol. 2017 Dec 28;9(36):1385-1388. doi: 10.4254/wjh.v9.i36.1385.

Abstract

Eosinophilic cholangitis is a rare cause of deranged obstructive liver function tests. It has been described as a great mimicker for malignant biliary strictures and bile duct obstruction. There are only case reports available on treatment experience for eosinophilic cholangitis. A large proportion of patients present with biliary strictures for which they have undergone surgery or endoscopic treatment and a small proportion was given systemic corticosteroid. We share our treatment experience using budesonide which has fewer systemic side effects to prednisolone and avoids invasive management.

摘要

嗜酸性胆管炎是肝功能检查异常伴梗阻的一种罕见病因。它被描述为恶性胆管狭窄和胆管梗阻的重要模仿者。目前仅有关于嗜酸性胆管炎治疗经验的病例报告。很大一部分患者存在胆管狭窄并接受了手术或内镜治疗,少数患者接受了全身性皮质类固醇治疗。我们分享使用布地奈德的治疗经验,布地奈德的全身副作用比泼尼松龙少,且避免了侵入性治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39f4/5756730/0cebdef529a1/WJH-9-1385-g001.jpg

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