Akolkar Shalaka, Patel Jalpa, Abdu Backer, Sorser Serge
Division of Gastroenterology, Internal Medicine, Michigan State University-Providence Park Hospital, Southfield, MI.
ACG Case Rep J. 2019 Nov 28;6(11):e00235. doi: 10.14309/crj.0000000000000235. eCollection 2019 Nov.
Often, when biliary strictures are evaluated, malignancy is high on the differential. However, it is important to consider benign and malignant causes because approximately 10% of biliary strictures are benign. Eosinophilic cholangitis is an extremely rare benign disorder of the biliary tract caused by fibrosis and stricture from eosinophilic infiltration. The etiology of the disease remains unclear, and often, patients present with obstructive jaundice. We present a young man who presented with obstructive jaundice and abdominal pain, with a biliary stricture and peripheral eosinophilia. The final surgical pathology revealed eosinophilic cholangitis.
通常，在评估胆管狭窄时，恶性肿瘤在鉴别诊断中占很大比重。然而，考虑良性和恶性病因很重要，因为约10%的胆管狭窄是良性的。嗜酸性胆管炎是一种极为罕见的良性胆道疾病，由嗜酸性粒细胞浸润导致的纤维化和狭窄引起。该病的病因尚不清楚，患者常表现为梗阻性黄疸。我们报告一名年轻男性，他因梗阻性黄疸和腹痛就诊，伴有胆管狭窄和外周嗜酸性粒细胞增多。最终手术病理显示为嗜酸性胆管炎。
