Bangalore-Yogananda Chandan-Ganesh, Rosenberry Ryan, Soni Sagar, Liu Hanli, Nelson Michael D, Tian Fenghua
Department of Bioengineering, The University of Texas at Arlington, 500 UTA Blvd., Arlington, TX 76010, USA.
Department of Kinesiology, The University of Texas at Arlington, 411 S. Nedderman Dr., Arlington, TX 76010, USA.
Biomed Opt Express. 2017 Dec 8;9(1):131-141. doi: 10.1364/BOE.9.000131. eCollection 2018 Jan 1.
Noninvasive, direct measurement of local muscle blood flow in humans remains limited. Diffuse correlation spectroscopy (DCS) is an emerging technique to measure regional blood flow at the microvascular level. In order to better understand the strengths and limitations of this novel technique, we performed a validation study by comparing muscle blood flow changes measured with DCS and Doppler ultrasound during exercise. Nine subjects were measured (all males, 27.4 ± 2.9 years of age) for a rhythmic handgrip exercise at 20% and 50% of individual maximum voluntary contraction (MVC), followed by a post-exercise recovery. The results from DCS and Doppler ultrasound were highly correlated ( = 0.99 ± 0.02). DCS was more reliable and less susceptible to motion artifact.
在人体中对局部肌肉血流进行无创、直接测量的方法仍然有限。扩散相关光谱技术(DCS)是一种用于在微血管水平测量局部血流的新兴技术。为了更好地理解这项新技术的优势和局限性,我们进行了一项验证研究,比较了在运动过程中通过DCS和多普勒超声测量的肌肉血流变化。对9名受试者(均为男性,年龄27.4±2.9岁)进行了研究,让他们以个人最大自主收缩(MVC)的20%和50%进行有节奏的握力运动,随后进行运动后恢复。DCS和多普勒超声的结果高度相关(=0.99±0.02)。DCS更可靠,且更不易受运动伪影影响。