Carp Stefan A, Robinson Mitchell B, Franceschini Maria A
Massachusetts General Hospital, Harvard Medical School, Optics at Martinos Research Group, Charlestown, Massachusetts, United States.
Neurophotonics. 2023 Jan;10(1):013509. doi: 10.1117/1.NPh.10.1.013509. Epub 2023 Jan 24.
Diffuse correlation spectroscopy (DCS) has emerged as a versatile, noninvasive method for deep tissue perfusion assessment using near-infrared light. A broad class of applications is being pursued in neuromonitoring and beyond. However, technical limitations of the technology as originally implemented remain as barriers to wider adoption. A wide variety of approaches to improve measurement performance and reduce cost are being explored; these include interferometric methods, camera-based multispeckle detection, and long path photon selection for improved depth sensitivity. We review here the current status of DCS technology and summarize future development directions and the challenges that remain on the path to widespread adoption.
扩散相关光谱法(DCS)已成为一种通用的、非侵入性的方法,用于使用近红外光进行深部组织灌注评估。目前正在神经监测及其他领域探索广泛的应用。然而,最初实施的该技术的技术局限性仍然是其更广泛应用的障碍。目前正在探索各种提高测量性能和降低成本的方法;这些方法包括干涉测量法、基于相机的多散斑检测以及用于提高深度灵敏度的长路径光子选择。我们在此回顾DCS技术的现状,并总结未来的发展方向以及在广泛应用道路上仍然存在的挑战。