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.的生物学特性与致病性

Biological characteristics and pathogenicity of .

作者信息

Wang Yuehua, Jiang Linzhe, Zhao Yitong, Ju Xiaohong, Wang Le, Jin Liang, Fine Ryan D, Li Mingguang

机构信息

College of Laboratory Medicine, Jilin Medical University, Jilin City, China.

General Surgery, Jilin People's Hospital, Jilin City, China.

出版信息

Front Microbiol. 2023 Apr 5;14:1147077. doi: 10.3389/fmicb.2023.1147077. eCollection 2023.

Abstract

is an opportunistic protozoa, which exists widely in nature and is mainly distributed in soil and water. usually exists in two forms, trophozoites and cysts. The trophozoite stage is one of growth and reproduction while the cyst stage is characterized by cellular quiescence, commonly resulting in human infection, and the lack of effective monotherapy after initial infection leads to chronic disease. can infect several human body tissues such as the skin, cornea, conjunctiva, respiratory tract, and reproductive tract, especially when the tissue barriers are damaged. Furthermore, serious infections can cause keratitis, granulomatous amoebic encephalitis, skin, and lung infections. With an increasing number of infections in recent years, the pathogenicity of is becoming more relevant to mainstream clinical care. This review article will describe the etiological characteristics of infection in detail from the aspects of biological characteristic, classification, disease, and pathogenic mechanism in order to provide scientific basis for the diagnosis, treatment, and prevention of infection.

摘要

是一种机会性原生动物,广泛存在于自然界,主要分布在土壤和水中。通常以滋养体和包囊两种形式存在。滋养体阶段是生长和繁殖阶段,而包囊阶段的特征是细胞静止,通常会导致人类感染,初次感染后缺乏有效的单一疗法会导致慢性病。可感染人体的多个组织,如皮肤、角膜、结膜、呼吸道和生殖道,尤其是当组织屏障受损时。此外,严重感染可导致角膜炎、肉芽肿性阿米巴脑炎、皮肤和肺部感染。近年来随着感染病例的增加,其致病性与主流临床护理的相关性越来越高。这篇综述文章将从生物学特性、分类、疾病和致病机制等方面详细描述感染的病因特征,以便为感染的诊断、治疗和预防提供科学依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0631/10113681/c0b3d0ec8a25/fmicb-14-1147077-g001.jpg

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