Dalia Tarun, Tuffaha Ahmad M
Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA.
Department of Nephrology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Hemodial Int. 2018 Jul;22(3):E39-E44. doi: 10.1111/hdi.12635. Epub 2018 Jan 23.
Dialysis disequilibrium syndrome (DDS) is a rare central nervous system (CNS) disease which develops in patients receiving hemodialysis (HD). Although it has been reported in patients receiving chronic HD, DDS is more common during or immediately after the first HD treatment. The exact incidence of DDS is unknown. Death in DDS is an extremely rare phenomenon and to the best of our knowledge only 9 cases have been reported showing this association. We present a unique case of a 42-year-old female on chronic HD, and no prior history of CNS disease, who developed brain death in the setting of DDS 2 hours into the dialysis treatment. A literature review of all previously reported cases was performed.
透析失衡综合征（DDS）是一种罕见的中枢神经系统（CNS）疾病，发生于接受血液透析（HD）的患者。虽然在接受慢性血液透析的患者中已有报道，但DDS在首次血液透析治疗期间或刚结束后更为常见。DDS的确切发病率尚不清楚。DDS导致死亡是极为罕见的现象，据我们所知，仅有9例显示存在这种关联的病例报道。我们报告了一例独特的病例，一名42岁的女性，长期接受血液透析，既往无中枢神经系统疾病史，在透析治疗开始2小时后因DDS导致脑死亡。我们对所有先前报道的病例进行了文献综述。
