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使用基质辅助激光解吸电离飞行时间质谱的新开发商业检测方法检测碳青霉烯酶

Detection of carbapenemases with a newly developed commercial assay using Matrix Assisted Laser Desorption Ionization-Time of Flight.

作者信息

Rapp Ellionor, Samuelsen Ørjan, Sundqvist Martin

机构信息

Department of Laboratory Medicine, Clinical Microbiology University Hospital, SE-701 85 Örebro, Sweden.

Norwegian National Advisory Unit on Detection of Antimicrobial Resistance, Department of Microbiology and Infection Control, University Hospital of North Norway, Tromsø, Norway; Microbial Pharmacology and Population Biology Research Group, Department of Pharmacy, UiT The Arctic University of Norway, Tromsø, Norway.

出版信息

J Microbiol Methods. 2018 Mar;146:37-39. doi: 10.1016/j.mimet.2018.01.008. Epub 2018 Feb 3.

DOI:10.1016/j.mimet.2018.01.008
PMID:29360488
Abstract

This study evaluated the performance of the MBT STAR-Carba kit (Bruker Daltonics), to detect carbapenemase producing Enterobacteriaceae, Pseudomonas aeruginosa and Acinetobacter spp. in comparison with the RAPIDEC® CARBA NP test (BioMerieux). MBT STAR-Carba allowed the detection of carbapenemases in Enterobacteriaceae and P. aeruginosa.

摘要

本研究评估了MBT STAR - Carba试剂盒(布鲁克道尔顿公司)检测产碳青霉烯酶肠杆菌科细菌、铜绿假单胞菌和不动杆菌属的性能,并与RAPIDEC® CARBA NP检测法(生物梅里埃公司)进行比较。MBT STAR - Carba能够检测肠杆菌科细菌和铜绿假单胞菌中的碳青霉烯酶。

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