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姜黄素的生理效应综合评价

A Comprehensive Review on Physiological Effects of Curcumin.

机构信息

Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India.

Department of Zoology, Lucknow University, Lucknow, India.

出版信息

Drug Res (Stuttg). 2020 Oct;70(10):441-447. doi: 10.1055/a-1207-9469. Epub 2020 Aug 3.

DOI:10.1055/a-1207-9469
PMID:32746480
Abstract

Turmeric ( Linn) is an herbal medicine which is traditionally used as a spice, food colouring or flavouring agent and widely used for several diseases such as biliary disorders, cough, hepatic disorders, rheumatism, wound healing, sinusitis, diabetes, cardiac disorders and neurological disorder. It belongs to the family. Turmeric is a popular domicile remedy used in Indian food, is mainly a native of south-east Asia, is widely cultivated in India, Sri Lanka, Indonesia, China, Jamaica , Peru, Haiti and Taiwan and it is very less expensive. Curcumin is the main principle of turmeric. Curcumin has shown various biological properties pre-clinically and clinically. Curcumin is a highly pleiotropic molecule which can be modulators of various intracellular signalling pathways that maintain cell growth. It has been reported as anti-inflammatory, anti-angiogenic, antioxidant, wound healing, anti-cancer, anti-Alzheimer and anti-arthritis and possesses an excellent safety profile. All previous review articles on curcumin have collected the biological/pharmacological activities but this review article summarises the most interesting in vitro and in vivo studies of curcumin on most running diseases around the whole world.

摘要

姜黄(Linn)是一种草药,传统上用作香料、食用色素或调味剂,广泛用于多种疾病,如胆道疾病、咳嗽、肝脏疾病、风湿病、伤口愈合、鼻窦炎、糖尿病、心脏疾病和神经障碍。它属于姜科。姜黄是一种流行的家庭疗法,用于印度食物,主要原产于东南亚,在印度、斯里兰卡、印度尼西亚、中国、牙买加、秘鲁、海地和中国台湾广泛种植,价格非常便宜。姜黄素是姜黄的主要成分。姜黄素在临床前和临床阶段表现出多种生物学特性。姜黄素是一种高度多效的分子,可以作为各种维持细胞生长的细胞内信号通路的调节剂。它已被报道具有抗炎、抗血管生成、抗氧化、伤口愈合、抗癌、抗老年痴呆症和抗关节炎作用,并且具有极好的安全性。之前所有关于姜黄素的综述文章都收集了其生物学/药理学活性,但这篇综述文章总结了姜黄素在全球范围内针对大多数正在进行的疾病的最有趣的体外和体内研究。

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1
A Comprehensive Review on Physiological Effects of Curcumin.姜黄素的生理效应综合评价
Drug Res (Stuttg). 2020 Oct;70(10):441-447. doi: 10.1055/a-1207-9469. Epub 2020 Aug 3.
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Turmeric and Curcumin: From Traditional to Modern Medicine.姜黄和姜黄素:从传统医学到现代医学。
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Curcumin, an active component of turmeric (Curcuma longa), and its effects on health.姜黄中的一种活性成分——姜黄素及其对健康的影响。
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Multitargeting by turmeric, the golden spice: From kitchen to clinic.姜黄,金色香料的多靶点作用:从厨房到临床。
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[Neuroprotective effects of curcumin].[姜黄素的神经保护作用]
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Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.姜黄提取物和姜黄素缓解关节性关节炎症状的疗效:随机临床试验的系统评价和荟萃分析
J Med Food. 2016 Aug;19(8):717-29. doi: 10.1089/jmf.2016.3705.

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Curcumin, a bioactive compound of Turmeric (Curcuma longa) and its derivatives as α-amylase and α-glucosidase inhibitors.姜黄素是姜黄(Curcuma longa)的一种生物活性化合物,及其衍生物可作为α-淀粉酶和α-葡萄糖苷酶抑制剂。
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