Navsaria Pradeep, Nicol Andrew, Krige Jake, Edu Sorin, Chowdhury Sharfuddin
Trauma Center, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa.
Surgical Gastroenterology, University of Cape Town , Cape Town, South Africa.
Eur J Trauma Emerg Surg. 2019 Apr;45(2):323-328. doi: 10.1007/s00068-018-0913-z. Epub 2018 Jan 24.
Nonoperative management (NOM) of gunshot liver injuries (GLI) is infrequently practiced. The aim of this study was to assess the safety of selective NOM of GLI.
A prospective, protocol-driven study, which included patients with GLI admitted to a level 1 trauma center, was conducted over a 52-month period. Stable patients without peritonism or sustained hypotension with right-sided thoracoabdominal (RTA) and right upper quadrant (RUQ), penetrating wounds with or without localized RUQ tenderness, underwent contrasted abdominal CT scan to determine the trajectory and organ injury. Patients with established liver and/or kidney injuries, without the evidence of hollow viscus injury, were observed with serial clinical examinations. Outcome parameters included the need for delayed laparotomy, complications, the length of hospital stay and survival.
During the study period, 54 (28.3%) patients of a cohort of 191 patients with GLI were selected for NOM of hemodynamic stability, the absence of peritonism and CT imaging. The average Revised Trauma Score (RTS) and Injury Severity Score (ISS) were 7.841 and 25 (range 4-50), respectively. 21 (39%) patients had simple (Grades I and II) and 33 (61%) patients sustained complex (Grades III to V) liver injuries. Accompanying injuries included 12 (22.2%) kidney, 43 (79.6%) diaphragm, 20 (37.0%) pulmonary contusion, 38 (70.4%) hemothoraces, and 24 (44.4%) rib fractures. Three patients required delayed laparotomy resulting in an overall success of NOM of 94.4%. Complications included: liver abscess (1), biliary fistula (5), intrahepatic A-V fistula (1) and hospital-acquired pneumonia (3). The overall median hospital stay was 6 (IQR 4-11) days, with no deaths.
The NOM of carefully selected patients with GLI is safe and associated with minimal morbidity.
肝枪伤(GLI)的非手术治疗(NOM)较少应用。本研究旨在评估GLI选择性NOM的安全性。
在52个月的时间里,开展了一项前瞻性、遵循方案的研究,纳入了入住一级创伤中心的GLI患者。对于没有腹膜炎或持续性低血压、右侧胸腹(RTA)和右上腹(RUQ)有穿透伤且有或无局限性RUQ压痛的稳定患者,进行腹部增强CT扫描以确定弹道和器官损伤情况。对于已确诊有肝和/或肾损伤但无中空脏器损伤证据的患者,通过系列临床检查进行观察。观察指标包括延迟剖腹手术的必要性、并发症、住院时间和生存率。
在研究期间,191例GLI患者中有54例(28.3%)因血流动力学稳定、无腹膜炎及CT影像表现而被选择进行NOM。平均修正创伤评分(RTS)和损伤严重度评分(ISS)分别为7.841和25(范围4 - 50)。21例(39%)患者为单纯性(I级和II级)肝损伤,33例(61%)患者为复杂性(III级至V级)肝损伤。伴随损伤包括12例(22.2%)肾损伤、43例(79.6%)膈肌损伤、20例(37.0%)肺挫伤、38例(70.4%)血胸和24例(44.4%)肋骨骨折。3例患者需要延迟剖腹手术,NOM的总体成功率为94.4%。并发症包括:肝脓肿(1例)、胆瘘(5例)、肝内动静脉瘘(1例)和医院获得性肺炎(3例)。总体中位住院时间为6天(四分位间距4 - 11天),无死亡病例。
对精心挑选的GLI患者进行NOM是安全的,且发病率极低。