Filosa Alessandra, Filosa Giorgio
Anatomic Pathology, Hospital of Macerata, AREA Vasta 3 ASUR Marche, Macerata, Italy.
Unit of Dermatology, Carlo Urbai Hospital, AREA Vasta 2 ASUR Marche, Jesi, Ancona, Italy -
G Ital Dermatol Venereol. 2018 Apr;153(2):265-272. doi: 10.23736/S0392-0488.18.05841-8. Epub 2018 Jan 24.
The neutrophilic dermatoses (NDs) comprise a group of heterogeneous disorders characterized by inflammatory skin lesions that histologically show an intense inflammatory infiltrate composed primarily by neutrophils, with no evidence of infection or vasculitis. Although there are distinct clinical differences in the classical lesions of these disorders, many patients have overlapping features. In this review, we describe the clinical aspects of the main NDs, including: Sweet Syndrome, ND of the dorsal hands, pyoderma gangrenosum, erythema elevatum diutinum, subcorneal pustular dermatosis, neutrophilic eccrine hidradenitis, rheumatoid neutrophilic dermatitis, neutrophilic panniculitis, and aseptic abscesses including their association with underlying diseases and the differential diagnoses.
嗜中性皮肤病(NDs)是一组异质性疾病,其特征为炎症性皮肤病变,组织学上表现为主要由中性粒细胞组成的强烈炎症浸润,且无感染或血管炎的证据。尽管这些疾病的典型病变在临床上存在明显差异,但许多患者具有重叠特征。在本综述中,我们描述了主要嗜中性皮肤病的临床方面,包括:Sweet综合征、手背嗜中性皮肤病、坏疽性脓皮病、持久性隆起性红斑、角层下脓疱性皮肤病、嗜中性小汗腺炎、类风湿性嗜中性皮肤病、嗜中性脂膜炎以及无菌性脓肿,包括它们与潜在疾病的关联和鉴别诊断。