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解读脓疱型坏疽性脓皮病的组织病理学:一种多学科诊断方法

Decoding the Histopathology of Pustular Pyoderma Gangrenosum: A Multidisciplinary Approach to Diagnosis.

作者信息

Bavikar Rupali, Singh Dipti

机构信息

Pathology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.

出版信息

Cureus. 2024 Aug 17;16(8):e67059. doi: 10.7759/cureus.67059. eCollection 2024 Aug.

Abstract

This article discusses the rare neutrophilic dermatosis pustular pyoderma gangrenosum (PG), characterized by necrotizing skin lesions. It highlights the importance of thorough histological examination in diagnosing this variation, which resembles other pustular dermatoses. The case study of a 54-year-old female highlights the unique histological aspects of PG, including epidermal erosion, neutrophilic infiltration, sterile abscesses, and no vasculitis. The article emphasizes the need for differential diagnosis and clinical correlation, emphasizing the importance of collaboration between physicians and pathologists for accurate diagnosis.

摘要

本文讨论了罕见的嗜中性皮病——坏疽性脓皮病(PG),其特征为坏死性皮肤病变。文中强调了全面组织学检查在诊断这种与其他脓疱性皮肤病相似的变异型疾病中的重要性。一名54岁女性的病例研究突出了PG独特的组织学特征,包括表皮糜烂、嗜中性粒细胞浸润、无菌性脓肿且无血管炎。本文强调了鉴别诊断和临床关联的必要性,强调了医生与病理学家合作以进行准确诊断的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ac1/11403648/771858f18556/cureus-0016-00000067059-i01.jpg

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