Badakere Swathi Vallabh, Choudhari Nikhil S, Rao Harsha L, Chary C Raghava, Garudadri Chandra Sekhar, Senthil Sirisha
VST Centre for Glaucoma Care, L. V. Prasad Eye Institute, Hyderabad, Telangana, India.
Department of Glaucoma, Narayana Nethralaya, Bengaluru, Karnataka, India *
Optom Vis Sci. 2018 Feb;95(2):129-135. doi: 10.1097/OPX.0000000000001174.
Measuring the intraocular pressure (IOP) on the sclera can be an alternative to conventional corneal measurement in eyes with scarred corneas. However, these measurements have to be evaluated prior in normal eyes. Our study aimed to evaluate scleral IOP using Tono-Pen and compared it with corneal Goldmann applanation measurements.
The aim of this study was to evaluate the ability of limbal and scleral Tono-Pen IOP readings to predict central corneal Goldmann applanation tonometry (GAT) readings in eyes with normal corneas.
In a cross-sectional study, 115 eyes of 115 patients attending a tertiary eye care center underwent GAT on the central cornea followed by Tono-Pen readings at the central cornea, at the limbus, and at the sclera. Bland-Altman plots were used to determine the agreement between different methods of IOP measurement.
The median IOP (interquartile range) by GAT performed on the central cornea was 18 (16, 24) mmHg, and the IOP ranged from 10 to 54 mmHg. The median IOPs (interquartile range) by Tono-Pen obtained at central cornea, limbus, and sclera were 16 (13, 23), 23 (17, 28), and 33 (27, 44) mmHg, respectively. The Pearson correlation coefficient and the 95% limits of agreement between GAT readings and Tono-Pen readings at the central cornea were 0.9 (P < .001) and -4.9 to 8.74 mmHg, respectively. The correlation coefficient between GAT readings and Tono-Pen readings at the limbus and GAT readings and Tono-Pen readings at the sclera was 0.46 (P < .001) and 0.23 (P = .01), respectively. The 95% limits of agreement between these pairs of readings were -20.55 to 13.66 and -44.02 to 13.37 mmHg, respectively.
This study showed limited ability of Tono-Pen readings obtained at the limbus and sclera to predict the central corneal GAT IOP readings in eyes with normal corneas at various IOP ranges.
对于角膜瘢痕化的眼睛,在巩膜上测量眼压(IOP)可作为传统角膜测量的替代方法。然而,这些测量必须先在正常眼睛中进行评估。我们的研究旨在使用眼压笔评估巩膜眼压,并将其与角膜Goldmann压平测量结果进行比较。
本研究的目的是评估在正常角膜的眼睛中,角膜缘和巩膜眼压笔测量的眼压读数预测中央角膜Goldmann压平眼压计(GAT)读数的能力。
在一项横断面研究中,115名在三级眼科护理中心就诊的患者的115只眼睛先进行中央角膜GAT测量,然后在中央角膜、角膜缘和巩膜处进行眼压笔读数。使用Bland-Altman图来确定不同眼压测量方法之间的一致性。
中央角膜GAT测量的眼压中位数(四分位间距)为18(16,24)mmHg,眼压范围为10至54 mmHg。眼压笔在中央角膜、角膜缘和巩膜处获得的眼压中位数(四分位间距)分别为16(13,23)、23(17,28)和33(27,44)mmHg。中央角膜处GAT读数与眼压笔读数之间的Pearson相关系数和95%一致性界限分别为0.9(P <.001)和-4.9至8.74 mmHg。角膜缘处GAT读数与眼压笔读数之间以及巩膜处GAT读数与眼压笔读数之间的相关系数分别为0.46(P <.001)和0.23(P =.01)。这两组读数之间的95%一致性界限分别为-20.55至13.66和-44.02至13.37 mmHg。
本研究表明,在不同眼压范围内,角膜缘和巩膜处的眼压笔读数预测正常角膜眼睛中央角膜GAT眼压读数的能力有限。