Department of Ophthalmology, Faculty of Medicine, Prince of Songkla University, Hatyai, Songkhla Province, Thailand.
J Glaucoma. 2021 Apr 1;30(4):317-324. doi: 10.1097/IJG.0000000000001725.
Edematous corneas had lower Goldmann applanation tonometer (GAT) intraocular pressure (IOP) compared with other tonometers. A significant, mild negative correlation between central corneal thickness (CCT) and GAT IOP was found in a group of significant edematous corneas with CCT increases of >100 µm.
To compare the IOP that was randomly obtained with the GAT, Tono-Pen, iCare, and Pascal dynamic contour tonometer in patients with corneal edema after phacoemulsification.
Corneal edema was quantified by CCT measurement. The agreement between IOP measurements assessed by different instruments was evaluated using Bland-Altman plots. The relationship between CCT and IOP was investigated using the coefficient of correlation. The CCT and IOP were compared between the periods of postsurgical edema and after its resolution.
The mean age of 60 patients was 75.9±7.8 years. CCT increased significantly after surgery, by an average of 96.1±39.9 µm (P<0.001). Relative to the IOPs measured with the GAT in edematous eyes: the mean difference in Tono-Pen IOPs was 4.7 mm Hg; 95% limits of agreement (LOA), -0.3 to 9.6 mm Hg. For iCare, was 2.3 mm Hg; 95% LOA, -2.2 to 6.8 mm Hg. For Pascal dynamic contour tonometer, was 3.0 mm Hg; 95% LOA, -0.4 to 6.5 mm Hg. Edematous corneas had significantly lower GAT IOP than Tono-Pen IOP; 12.3±3.2 versus 16.9±3.1 (P=0.02). Pearson correlation coefficients (r) showed a high correlation between the 4 tonometers in eyes without edema. There was a significant, mild negative correlation between CCT and GAT IOP (r=-0.25, P=0.02) in a group of significant edematous corneas with CCT increases of >100 µm: GAT IOP decreased by 3.1 mm Hg for every 10-µm increase in CCT.
IOP readings with GAT tended to be lower than those obtained with the other tonometers, especially the Tono-Pen. GAT IOP readings in cases of severe corneal edema should be interpreted with caution.
与其他眼压计相比,水肿角膜的 Goldmann 压平眼压计(GAT)眼压较低。在一组中央角膜厚度(CCT)增加超过 100μm 的明显水肿角膜中,发现 CCT 与 GAT 眼压之间存在显著、轻度的负相关。
比较白内障超声乳化术后角膜水肿患者随机使用 GAT、Tono-Pen、iCare 和 Pascal 动态轮廓眼压计测量的眼压。
通过 CCT 测量量化角膜水肿。使用 Bland-Altman 图评估不同仪器测量的眼压的一致性。使用相关系数研究 CCT 与眼压之间的关系。比较术后水肿期和水肿消退后的 CCT 和眼压。
60 例患者的平均年龄为 75.9±7.8 岁。术后 CCT 显著增加,平均增加 96.1±39.9μm(P<0.001)。与水肿眼中 GAT 测量的眼压相比:Tono-Pen 眼压的平均差值为 4.7mmHg;95%置信区间(LOA)为-0.3 至 9.6mmHg。iCare 的差值为 2.3mmHg;95% LOA 为-2.2 至 6.8mmHg。对于 Pascal 动态轮廓眼压计,差值为 3.0mmHg;95% LOA 为-0.4 至 6.5mmHg。水肿角膜的 GAT 眼压明显低于 Tono-Pen 眼压;12.3±3.2 与 16.9±3.1(P=0.02)。在没有水肿的眼睛中,Pearson 相关系数(r)显示四种眼压计之间具有高度相关性。在一组 CCT 增加超过 100μm 的明显水肿角膜中,存在 CCT 与 GAT 眼压之间显著、轻度的负相关(r=-0.25,P=0.02):CCT 每增加 10μm,GAT 眼压下降 3.1mmHg。
与其他眼压计相比,GAT 眼压读数往往较低,尤其是 Tono-Pen。应谨慎解释严重角膜水肿病例的 GAT 眼压读数。