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[甲状腺癌扩展pTNM分类的建议:对TNM分类第8版缺陷的评论(德文版)]

[Proposal for an extended pTNM classification of thyroid carcinoma : Commentary on deficits of the 8th edition of the TNM classification (German version)].

作者信息

Schmid K W, Synoracki S, Dralle H, Wittekind C

机构信息

Institut für Pathologie, Universitätsklinikum Essen, Universität Duisburg-Essen, Hufelandstraße 55, 45147, Essen, Deutschland.

Westdeutsches Tumorzentrum Essen (WTZ), Essen, Deutschland.

出版信息

Pathologe. 2018 Feb;39(1):49-56. doi: 10.1007/s00292-017-0410-x.

Abstract

In the 8th edition of the TNM classification of thyroid carcinomas, which was introduced in 2017, carcinomas with minimal extrathyroidal extension are no longer mentioned, which might cause problems. These tumors were explicitly categorized in previous TNM classifications (5-7th editions). Studies on the prognostic relevance of minimal extrathyroidal extension have shown conflicting results. Moreover, the vast majority of these studies retrospectively analyzed only subgroups of thyroid carcinomas (e.g. differentiated thyroid carcinoma, papillary thyroid carcinoma). The proposed subcategorization of the current TNM classification (8th edition) ensures the continuity of the parameter minimal extrathyroidal extension within the TNM categorization of thyroid carcinomas and also offers the possibility to prospectively analyze in a standardized manner the potential biological relevance of minimal extrathyroidal extension in relation to tumor categories (T/pT category).

摘要

在2017年引入的甲状腺癌TNM分类第8版中,未再提及甲状腺外扩展极小的癌,这可能会引发问题。这些肿瘤在之前的TNM分类(第5 - 7版)中被明确分类。关于甲状腺外扩展极小的预后相关性研究结果相互矛盾。此外,这些研究绝大多数仅对甲状腺癌的亚组(如分化型甲状腺癌、乳头状甲状腺癌)进行了回顾性分析。当前TNM分类(第8版)提议的亚分类确保了甲状腺外扩展极小这一参数在甲状腺癌TNM分类中的连续性,并且还提供了以前瞻性、标准化方式分析甲状腺外扩展极小相对于肿瘤类别(T/pT类别)的潜在生物学相关性的可能性。

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