DNA中的内部运动。
Internal motions in DNA.
作者信息
Hogan M E, Jardetzky O
出版信息
Proc Natl Acad Sci U S A. 1979 Dec;76(12):6341-5. doi: 10.1073/pnas.76.12.6341.
Abstract
We have measured the 31P and 1H NMR parameters of fractionated double-stranded DNA fragments 600, 300, and 150 base pairs long. The results indicate that, inside an intact double helix, both the deoxyribose and the sugar-phosphate backbone of the helix fluctuate substantially from their equilibrium geometry. The time constant for those coupled motions is of the order of 1 nsec.
摘要
我们测量了长度为600、300和150个碱基对的双链DNA片段的31P和1H核磁共振参数。结果表明，在完整的双螺旋内部，脱氧核糖和螺旋的糖-磷酸骨架均与其平衡几何结构有显著波动。这些耦合运动的时间常数约为1纳秒。
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