Department of Biomedical Sciences, University of Padua, 35131 Padua, Italy.
Department of Biomedical Sciences, University of Padua, 35131 Padua, Italy; Department of Cell and Developmental Biology, Consortium for Mitochondrial Research, University College London, London WC1E 6BT, UK; The Francis Crick Institute, London NW1 1AT, UK.
Curr Biol. 2018 Jan 22;28(2):R73-R75. doi: 10.1016/j.cub.2017.11.040.
Many molecular and functional details of single events in mitochondrial dynamics have been reported, but little is known about their coordination. A recent study describes how cellular Ca signals, via remodelling the actin cytoskeleton, synchronise the formation of endoplasmic reticulum-mitochondria contacts with inner and outer mitochondrial membrane fission.
许多关于线粒体动力学中单事件的分子和功能细节已经被报道，但它们的协调机制知之甚少。最近的一项研究描述了细胞内 Ca 信号如何通过重塑肌动蛋白细胞骨架，使内质网-线粒体接触的形成与内外膜分裂同步。
