Schmitz Lauren L, Conley Dalton
Survey Research Center, Institute for Social Research, University of Michigan, 426 Thompson St., Ann Arbor, MI 48104, USA.
Department of Sociology, Princeton University. 153 Wallace Hall, Princeton, NJ 08544, USA.
Econ Educ Rev. 2017 Dec;61:85-97. doi: 10.1016/j.econedurev.2017.10.001. Epub 2017 Oct 7.
This study examines whether draft lottery estimates of the causal effects of Vietnam-era military service on schooling vary by an individual's genetic propensity toward educational attainment. To capture the complex genetic architecture that underlies the bio-developmental pathways, behavioral traits and evoked environments associated with educational attainment, we construct polygenic scores (PGS) for respondents in the Health and Retirement Study (HRS) that aggregate thousands of individual loci across the human genome and weight them by effect sizes derived from a recent genome-wide association study (GWAS) of years of education. Our findings suggest veterans with below average PGSs for educational attainment may have completed fewer years of schooling than comparable non-veterans. On the other hand, we do not find any difference in the educational attainment of veterans and non-veterans with above average PGSs. Results indicate that public policies and exogenous environments may induce heterogeneous treatment effects by genetic disposition.
本研究考察了越南战争时期服役对教育影响的抽签估计是否因个人的教育成就遗传倾向而异。为了捕捉构成生物发育途径、行为特征和与教育成就相关的诱发环境基础的复杂遗传结构,我们为健康与退休研究(HRS)中的受访者构建了多基因分数(PGS),该分数汇总了人类基因组中的数千个个体基因座,并根据最近一项关于受教育年限的全基因组关联研究(GWAS)得出的效应大小对其进行加权。我们的研究结果表明,教育成就多基因分数低于平均水平的退伍军人完成的受教育年限可能比类似的非退伍军人少。另一方面,我们没有发现多基因分数高于平均水平的退伍军人和非退伍军人在教育成就上有任何差异。结果表明,公共政策和外部环境可能会因遗传倾向而产生异质性治疗效果。