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加纳中部地区非心脏手术患者的术前贫血及相关术后结局

Preoperative Anaemia and Associated Postoperative Outcomes in Noncardiac Surgery Patients in Central Region of Ghana.

作者信息

Amponsah Gladys, Charwudzi Alice

机构信息

Department of Anaesthesia and Pain Management, School of Medical Sciences, University of Cape Coast, Cape Coast, Ghana.

Department of Chemical Pathology, School of Medical Sciences, University of Cape Coast, Cape Coast, Ghana.

出版信息

Anesthesiol Res Pract. 2017;2017:7410960. doi: 10.1155/2017/7410960. Epub 2017 Dec 11.

Abstract

INTRODUCTION

Several studies suggest that preoperative anaemia (PA) is associated with adverse postoperative outcomes, but little is known about these outcomes in the Central Region of Ghana. This study aims to determine the prevalence of PA among noncardiac surgical patients and its implications for their postoperative outcomes.

METHODS

This study was designed as an observational study; data including demographics and clinical and laboratory results were collected from the patients' records and through interviews.

RESULTS

A total of 893 inpatient surgical cases undergoing elective and emergency operations, aged 15 years and above with mean age of 44.2 ± 17.0 yrs, were enrolled. The prevalence of PA was 54.3%, mostly microcytic with or without hypochromia (57.2%). The prevalence was higher in females than males ( ≤ 0.001). Preoperative anaemia was significantly associated with prolonged length of hospital stay (OR: 2.12 (95% CI: 1.49-3.10)). Allogeneic blood transfusion significantly prolonged the length of hospital stay (OR 4.48 (95% CI: 2.67-7.51)). 15.5% of the anaemic patients received oral iron supplements compared to 2.2% of nonanaemic patients ( ≤ 0.001).

CONCLUSION

Preoperative anaemia is common among noncardiac surgical patients. It is independently and significantly associated with prolonged hospital stay leading to the use of increased healthcare resources. It is also the main predictor for perioperative allogeneic blood transfusions and the use of haematinics.

摘要

引言

多项研究表明,术前贫血(PA)与术后不良结局相关,但在加纳中部地区,人们对这些结局知之甚少。本研究旨在确定非心脏外科手术患者中PA的患病率及其对术后结局的影响。

方法

本研究设计为观察性研究;通过查阅患者病历和访谈收集包括人口统计学、临床和实验室结果等数据。

结果

共纳入893例年龄在15岁及以上、平均年龄为44.2±17.0岁的择期和急诊手术住院患者。PA的患病率为54.3%,大多为伴有或不伴有低色素性的小细胞性贫血(57.2%)。女性患病率高于男性(P≤0.001)。术前贫血与住院时间延长显著相关(比值比:2.12(95%置信区间:1.49 - 3.10))。异体输血显著延长了住院时间(比值比4.48(95%置信区间:2.67 - 7.51))。15.5%的贫血患者接受了口服铁补充剂,而非贫血患者为2.2%(P≤0.001)。

结论

术前贫血在非心脏外科手术患者中很常见。它与住院时间延长独立且显著相关,导致医疗资源使用增加。它也是围手术期异体输血和补血剂使用的主要预测因素。

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