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小梁切除术治疗假性剥脱性青光眼和原发性开角型青光眼的长期效果比较。

Comparison of long-term results of trabeculectomy to treat pseudoexfoliative glaucoma and primary open angle glaucoma.

作者信息

Pelitli Gürlü Vuslat, Güçlü Hande, Özal Altan, Benian Ömer, Alimgil Levent

机构信息

Department of Ophthalmology, Trakya University Medical School, Edirne 22030, Turkey.

Department of Ophthalmology, Ekol Private Hospital, Edirne 22030, Turkey.

出版信息

Int J Ophthalmol. 2018 Jan 18;11(1):66-70. doi: 10.18240/ijo.2018.01.12. eCollection 2018.

Abstract

AIM

To compare the long term outcome of trabeculectomy in patients with pseudoexfoliative glaucoma (PEG) and primary open angle glaucoma (POAG) in terms of surgical success.

METHODS

The success of the trabeculectomy was evaluated by three criteria. Criterion A: intraocular pressure (IOP) ≤21 mm Hg and decrease in IOP ≥20%; Criterion B: IOP ≤18 mm Hg and decrease in IOP ≥30%; Criterion C: IOP ≤15 mm Hg and decrease in IOP ≥50%. Patients that met these criteria without medical treatment were considered to be completely successful, while those that met these criteria with medical treatment were considered partially successful. Significance levels of differences between the POAG and PEG groups in the Kaplan-Meier survival curves were calculated with the log-rank test.

RESULTS

Sixty-four eyes from 64 patients with PEG and 51 eyes from 51 patients with POAG were evaluated. No significant differences were detected between the PEG and POAG groups according to full or partial success relative to each of the three criteria (A: =0.73, 0.32; B: =0.73, 0.31; C:=0.90, 0.27).

CONCLUSION

There is no difference in the long-term success of trabeculectomy between PEG and POAG patients whose clinical characteristics are otherwise the same.

摘要

目的

比较假性剥脱性青光眼(PEG)患者和原发性开角型青光眼(POAG)患者小梁切除术的长期手术成功率。

方法

通过三项标准评估小梁切除术的成功率。标准A:眼压(IOP)≤21 mmHg且眼压降低≥20%;标准B:IOP≤18 mmHg且眼压降低≥30%;标准C:IOP≤15 mmHg且眼压降低≥50%。无需药物治疗即可达到这些标准的患者被视为完全成功,而需药物治疗才能达到这些标准的患者被视为部分成功。采用对数秩检验计算POAG组和PEG组在Kaplan-Meier生存曲线中的差异显著性水平。

结果

对64例PEG患者的64只眼和51例POAG患者的51只眼进行了评估。根据三项标准中的每一项,PEG组和POAG组在完全或部分成功方面均未检测到显著差异(标准A:P = 0.73,0.32;标准B:P = 0.73,0.31;标准C:P = 0.90,0.27)。

结论

临床特征相同的PEG患者和POAG患者小梁切除术的长期成功率无差异。

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