a Laboratorio de Toxicología Molecular, Centro de Investigación Aplicada en Ambiente y Salud (CIAAS), Coordinación para la Innovación y Aplicación de la Ciencia y la Tecnología (CIACYT) , Universidad Autónoma de San Luis Potosí . San Luis Potosí , México.
b Facultad de Medicina , Universidad Autónoma de San Luis Potosí . San Luis Potosí , México.
Int J Environ Health Res. 2018 Feb;28(1):90-101. doi: 10.1080/09603123.2018.1429578. Epub 2018 Jan 29.
The aim of this study was to perform a polybrominated diphenyl ethers (PBDEs) exposure assessment using blood samples collected from children living in the metropolitan area of Guadalajara, Jalisco, Mexico (GDL). Five congeners of PBDEs were analyzed using a gas chromatography/mass spectrometry technique. The blood concentrations of total PBDEs ranged from 5.50 to 169 ng/g lipid (42.0 ± 18.0 ng/g lipid; mean ± standard deviation). Regarding BDE congeners, the main congener (highest blood levels) was BDE99 (14.5 ± 5.50 ng/g lipid), followed by BDE100 (9.80 ± 3.40 ng/g lipid) and BDE154 (9.80 ± 5.90 ng/g lipid), and finally BDE153 (5.80 ± 2.30 ng/g lipid) and BDE47 (2.20 ± 1.20 ng/g lipid). In conclusion, blood PBDEs concentrations of concern were detected in this study, as blood levels were similar to the ones found in North America (the highest worldwide).
本研究旨在通过采集居住在墨西哥哈利斯科州瓜达拉哈拉大都市区的儿童血液样本进行多溴二苯醚（PBDEs）暴露评估。使用气相色谱/质谱技术分析了 5 种 PBDE 同系物。全 PBDEs 的血液浓度范围为 5.50 至 169ng/g 脂质（42.0±18.0ng/g 脂质；平均值±标准偏差）。关于 BDE 同系物，主要同系物（血液水平最高）为 BDE99（14.5±5.50ng/g 脂质），其次为 BDE100（9.80±3.40ng/g 脂质）和 BDE154（9.80±5.90ng/g 脂质），最后为 BDE153（5.80±2.30ng/g 脂质）和 BDE47（2.20±1.20ng/g 脂质）。总之，本研究检测到血液中存在令人关注的 PBDEs 浓度，因为血液水平与北美（全球最高）的水平相似。
