Kiadaliri A A, Uhlig T, Englund M
a Faculty of Medicine, Department of Clinical Sciences Lund, Orthopaedics, Clinical Epidemiology Unit , Lund University , Lund , Sweden.
b Department of Rheumatology, National Advisory Unit for Rehabilitation in Rheumatology , Diakonhjemmet Hospital , Oslo , Norway.
Scand J Rheumatol. 2018 Sep;47(5):410-417. doi: 10.1080/03009742.2017.1405461. Epub 2018 Jan 29.
To explore the burden of gout in the Nordic region, with a population around 27 million in 2015 distributed across six countries.
We used the findings of the 2015 Global Burden of Diseases study to report prevalence and disability associated with gout in the Nordic region.
From 1990 to 2015, the number of prevalent gout cases rose by 30% to 252 967 [95% uncertainty interval (UI) 223 478‒287 288] in the Nordic region. In 2015, gout contributed to 7982 (95% UI 5431‒10 800) years lived with disability (YLDs) in the region, an increase of 29% (95% UI 24‒35%) from 1990. While the crude YLD rate of gout increased by 12.9% (95% UI 7.8‒18.1%) between 1990 and 2015, the age-standardized YLD rate remained stable. Gout was ranked as the 63rd leading cause of total YLDs in the region in 2015, with the highest rank in men aged 55-59 years (38th leading cause of YLDs). The corresponding rank at the global level was 94. Of 195 countries studied, four Nordic countries [Greenland (2nd), Iceland (12th), Finland (14th), and Sweden (15th)] were among the top 15 countries with the highest age-standardized YLD rate of gout.
The burden of gout is rising in the Nordic region. Gout's contribution to the total burden of diseases in the region is more significant than the global average. Expected increases in gout burden owing to population growth and ageing call for stronger preventive and therapeutic strategies for gout management in Nordic countries.
探讨北欧地区痛风的负担情况，2015年该地区人口约2700万，分布在六个国家。
我们利用2015年全球疾病负担研究的结果报告北欧地区痛风的患病率和相关残疾情况。
1990年至2015年，北欧地区痛风的患病人数增加了30%，达到252967例[95%不确定区间（UI）223478 - 287288]。2015年，痛风导致该地区7982例（95% UI 5431 - 10800）伤残调整生命年（YLDs），较1990年增加了29%（95% UI 24 - 35%）。虽然痛风的粗YLD率在1990年至2015年间增加了12.9%（95% UI 7.8 - 18.1%），但年龄标准化YLD率保持稳定。2015年，痛风在该地区YLDs总数的主要病因中排名第63位，在55 - 59岁男性中排名最高（YLDs的第38大病因）。在全球层面的相应排名为第94位。在研究的195个国家中，四个北欧国家[格陵兰（第2位）、冰岛（第12位）、芬兰（第14位）和瑞典（第15位）]位列痛风年龄标准化YLD率最高的前15个国家。
北欧地区痛风负担正在上升。痛风对该地区疾病总负担的贡献比全球平均水平更为显著。由于人口增长和老龄化导致痛风负担预计增加一事，要求北欧国家采取更强有力的痛风管理预防和治疗策略。
