Trounson A, Howlett D, Rogers P, Hoppen H O
Fertil Steril. 1986 Apr;45(4):532-5. doi: 10.1016/s0015-0282(16)49283-6.
A randomized control trial involving 42 superovulated in vitro fertilization (IVF) patients was carried out to investigate the effects of providing supplementary progesterone (P) around the time of laparoscopy. P was given 12 to 15 hours and 1 hour before and 24 hours after laparoscopy in one group (group B); human chorionic gonadotropin was given 12 hours before laparoscopy in another group (group C); and the remainder received no treatment in addition to normal IVF procedures (group A). There was no difference in fertilization rate, the proportion of normally developing embryos, pregnancy rate, or birth rate between the treatment groups, We conclude that in the superovulation schedule used, P supplementation around the time of laparoscopy does not affect success rate of IVF.
一项涉及42名接受超排卵体外受精（IVF）的患者的随机对照试验开展，以研究在腹腔镜检查前后提供补充孕酮（P）的效果。一组（B组）在腹腔镜检查前12至15小时、1小时以及检查后24小时给予P；另一组（C组）在腹腔镜检查前12小时给予人绒毛膜促性腺激素；其余患者除正常IVF程序外未接受其他治疗（A组）。治疗组之间在受精率、正常发育胚胎比例、妊娠率或出生率方面没有差异。我们得出结论，在所采用的超排卵方案中，腹腔镜检查前后补充P不会影响IVF成功率。
