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Recent Taxonomic Developments with and Other Opportunistic Yeasts.与念珠菌及其他机会性酵母相关的近期分类学进展。
Curr Fungal Infect Rep. 2012 Sep;6(3):170-177. doi: 10.1007/s12281-012-0094-x.
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Detection of triazole resistance among Candida species by matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS).通过基质辅助激光解吸/电离飞行时间质谱（MALDI-TOF MS）检测念珠菌属中的三唑耐药性。
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Direct Identification of Urinary Tract Pathogens From Urine Samples Using the Vitek MS System Based on Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry.基于基质辅助激光解吸电离飞行时间质谱的Vitek MS系统直接从尿液样本中鉴定尿路病原体
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Genotypic Diversity Is Associated with Clinical Outcome and Phenotype in Cryptococcal Meningitis across Southern Africa.基因型多样性与南部非洲隐球菌性脑膜炎的临床结局和表型相关。
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Analysis of clinical and environmental Candida parapsilosis isolates by microsatellite genotyping--a tool for hospital infection surveillance.应用微卫星基因分型分析临床和环境近平滑念珠菌分离株-一种医院感染监测工具。
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Invasive Fungal Infections After Kidney Transplantation: A Single-center Experience.肾移植术后侵袭性真菌感染：单中心经验
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Identification of Haemophilus influenzae Type b Isolates by Use of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry.利用基质辅助激光解吸电离飞行时间质谱法鉴定b型流感嗜血杆菌分离株
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Development of a novel matrix-assisted laser desorption/ionization time-of-flight mass spectrum (MALDI-TOF-MS)-based typing method to identify meticillin-resistant Staphylococcus aureus clones.建立一种新型基质辅助激光解吸电离飞行时间质谱（MALDI-TOF-MS）分型方法，以鉴定耐甲氧西林金黄色葡萄球菌克隆。
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拓展基质辅助激光解吸电离飞行时间质谱的极限：超越真菌物种鉴定

Pushing the Limits of MALDI-TOF Mass Spectrometry: Beyond Fungal Species Identification.

作者信息

Rizzato Cosmeri, Lombardi Lisa, Zoppo Marina, Lupetti Antonella, Tavanti Arianna

机构信息

Department of Biology, University of Pisa, Via San Zeno 37, 56127 Pisa, Italy.

Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Via San Zeno 37, 56127 Pisa, Italy.

出版信息

J Fungi (Basel). 2015 Oct 16;1(3):367-383. doi: 10.3390/jof1030367.

DOI:10.3390/jof1030367
PMID:29376916
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5753130/
Abstract

Matrix assisted laser desorption ionization time of flight (MALDI-TOF) is a powerful analytical tool that has revolutionized microbial identification. Routinely used for bacterial identification, MALDI-TOF has recently been applied to both yeast and filamentous fungi, confirming its pivotal role in the rapid and reliable diagnosis of infections. Subspecies-level identification holds an important role in epidemiological investigations aimed at tracing virulent or drug resistant clones. This review focuses on present and future applications of this versatile tool in the clinical mycology laboratory.

摘要

基质辅助激光解吸电离飞行时间质谱（MALDI-TOF）是一种强大的分析工具，它彻底改变了微生物鉴定的方式。MALDI-TOF通常用于细菌鉴定，最近已应用于酵母和丝状真菌，证实了其在感染快速可靠诊断中的关键作用。亚种水平的鉴定在旨在追踪有毒或耐药克隆的流行病学调查中起着重要作用。本综述重点关注这种多功能工具在临床真菌学实验室中的当前和未来应用。