Lalhminghlui K, Jagetia Ganesh Chandra
Department of Zoology, Mizoram University, Tanhril, Aizawl-796 004 Mizoram, India.
Future Sci OA. 2018 Jan 4;4(2):FSO272. doi: 10.4155/fsoa-2017-0086. eCollection 2018 Feb.
Free radicals are an outcome of various metabolic activities and their excess production leads to many diseases. Therefore, it is necessary to neutralize excess free radicals.
MATERIALS & METHODS: Free-radical scavenging activity of various extracts of was evaluated using standard protocols.
Chloroform, ethanol and aqueous extracts of scavenged DPPH, hydroxyl, superoxide, nitric oxide and ABTS free radicals and increased ferric-reducing antioxidant potential in a concentration-dependent manner. A total of 1000 μg/ml of all the extracts and ethanol extract showed highest total flavonoids and phenol contents, respectively.
The different extracts of scavenged different free radicals efficiently due to the presence of flavonoids and polyphenols and may be helpful in free radical-induced diseases.
自由基是各种代谢活动的产物,其过量产生会导致多种疾病。因此,有必要中和过量的自由基。
使用标准方案评估了[具体名称未给出]各种提取物的自由基清除活性。
[具体名称未给出]的氯仿、乙醇和水提取物清除了二苯基苦味酰基自由基(DPPH)、羟基自由基、超氧阴离子自由基、一氧化氮自由基和2,2'-联氮-双-(3-乙基苯并噻唑啉-6-磺酸)二铵盐自由基(ABTS),并以浓度依赖的方式提高了铁还原抗氧化能力。所有提取物的总浓度为1000μg/ml时以及乙醇提取物分别显示出最高的总黄酮和酚类含量。
由于含有黄酮类化合物和多酚,[具体名称未给出]的不同提取物能有效清除不同的自由基,可能有助于治疗自由基诱导的疾病。