Sumiyoshi Chika, Takaki Manbu, Okahisa Yuko, Patterson Thomas L, Harvey Philip D, Sumiyoshi Tomiki
Faculty of Human Development and Culture, Fukushima University, 1 Kanayagawa, Fukushima, Fukushima, Japan, 960-1296.
Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Schizophr Res Cogn. 2014 Oct 12;1(3):137-143. doi: 10.1016/j.scog.2014.08.002. eCollection 2014 Sep.
The UCSD Performance-based Skills Assessment Brief (the UPSA-B) has been widely used for evaluating functional capacity in patients with schizophrenia. The utility of the battery in a wide range of cultural contexts has been of concern among developers. The current study investigated the validity of the Japanese version of the UPSA-B as a measure of functional capacity and as a co-primary for neurocognion. Sixty-four Japanese patients with schizophrenia and 83 healthy adults entered the study. The Japanese version of the UPSA-B (UPSA-B Japanese version) and the MATRICS Cognitive Consensus Battery Japanese version (MCCB Japanese version) were administered. Normal controls performed significantly better than patients, with large effect sizes for the Total and the subscale scores of the UPSA-B. Receiver Operating Characteristic (ROC) curve analysis revealed that the optimal cut-off point for the UPSA-B Total score was estimated at around 80. The UPSA-B Total score was significantly correlated with the MCCB Composite score and several domain scores, indicating the relationship between this co-primary measure and overall cognitive functioning in Japanese patients with schizophrenia. The results obtained here suggest that the UPSA-B Japanese version is an effective tool for evaluating disturbances of daily-living skills linked to cognitive functioning in schizophrenia, providing an identifiable cut-off point and relationships to neurocognition. Further research is warranted to evaluate the psychometrical properties and response to treatment of the Japanese version of the UPSA-B.
加州大学圣地亚哥分校基于表现的技能评估简表（UPSA-B）已被广泛用于评估精神分裂症患者的功能能力。开发者一直关注该测试组合在广泛文化背景下的效用。本研究调查了UPSA-B日语版作为功能能力测量工具以及作为神经认知共同主要指标的有效性。64名日本精神分裂症患者和83名健康成年人参与了这项研究。对他们施测了UPSA-B日语版和MATRICS认知共识测试组合日语版（MCCB日语版）。正常对照组的表现明显优于患者，UPSA-B总分及各分量表得分的效应量都很大。受试者工作特征（ROC）曲线分析显示，UPSA-B总分的最佳截断点估计约为80。UPSA-B总分与MCCB综合得分及几个领域得分显著相关，表明该共同主要指标与日本精神分裂症患者的整体认知功能之间存在关联。此处获得的结果表明，UPSA-B日语版是评估精神分裂症中与认知功能相关的日常生活技能障碍的有效工具，提供了一个可识别的截断点以及与神经认知的关系。有必要进一步研究以评估UPSA-B日语版的心理测量特性和对治疗的反应。
