用于评估临床缓解的一致性五因素阳性和阴性症状量表：对功能和认知表现的影响
Consensus five factor PANSS for evaluation of clinical remission: effects on functioning and cognitive performances.
作者信息
Pinna Federica, Bosia Marta, Cavallaro Roberto, Carpiniello Bernardo
机构信息
Department of Public Health. Clinical and Molecular Medicine-Section of Psychiatry, University of Cagliari, Via Liguria 13, 09127 Cagliari, Italy.
Department of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Via Stamira d'Ancona 20, 20127, Milan, Italy.
出版信息
Schizophr Res Cogn. 2014 Dec 8;1(4):187-192. doi: 10.1016/j.scog.2014.11.001. eCollection 2014 Dec.
UNLABELLED
Criteria developed by the Remission in Schizophrenia Working Group (RSWG), based upon 8 core symptoms of PANSS, are generally used for evaluation of Remission. However, some concerns have arisen as regard to the ability of the RSWG criteria to detect truly remitted cases. This study aims to compare the severity criteria of remission defined by the RSWG (RSWG-cr) with more restrictive criteria, based upon the use of PANSS factor model.
METHODS
112 chronic psychotic outpatients were examined. Symptomatic remission according to RSWGcr was compared with remission according to criteria based on the 20-items of PANSS considered in the consensus five factor model (PANSS-FCTcr), in relation to functional and neurocognitive outcomes.
RESULTS
Data from the study demonstrated the superiority of PANSS-FCTcr in identifying patients with higher functional and cognitive outcomes.
CONCLUSION
PANSS-FCTcr seems to be suitable for use in both common clinical practice and research setting, being associated with improved identification of truly remitted patients.
未标注
精神分裂症缓解工作组（RSWG）基于阳性和阴性症状量表（PANSS）的8个核心症状制定的标准，通常用于评估缓解情况。然而，对于RSWG标准检测真正缓解病例的能力已出现一些担忧。本研究旨在将RSWG定义的缓解严重程度标准（RSWG-cr）与基于PANSS因子模型使用的更严格标准进行比较。
方法
对112名慢性精神病门诊患者进行检查。将根据RSWGcr的症状缓解情况与根据基于共识五因子模型中考虑的PANSS的20项标准（PANSS-FCTcr）的缓解情况进行比较，涉及功能和神经认知结果。
结果
该研究数据证明了PANSS-FCTcr在识别具有更高功能和认知结果的患者方面的优越性。
结论
PANSS-FCTcr似乎适用于普通临床实践和研究环境，与更好地识别真正缓解的患者相关。
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