Tang Jianting, Lv Leiyang, Dai Xi-Jie, Li Chen-Chen, Li Lu, Li Chao-Jun
Department of Chemistry and FQRNT Centre for Green Chemistry and Catalysis, McGill University, 801 Sherbrook Street West, Montreal, Quebec H3A 0B8, Canada.
Chem Commun (Camb). 2018 Feb 13;54(14):1750-1753. doi: 10.1039/c7cc09290c.
Traditional cross-couplings require stoichiometric organometallic reagents. A novel nickel-catalyzed cross-coupling reaction between aldehydes and aryl halides via hydrazone intermediates has been developed, merging the Wolff-Kishner reduction and the classical cross-coupling reactions. Aromatic aldehydes, aryl iodides and aryl bromides are especially effective in this new cross-coupling chemistry.
传统的交叉偶联反应需要化学计量的有机金属试剂。人们开发了一种新型的镍催化醛与芳基卤化物之间通过腙中间体进行的交叉偶联反应，它将沃尔夫-基希纳还原反应与经典的交叉偶联反应结合在一起。芳香醛、芳基碘化物和芳基溴化物在这种新的交叉偶联化学中特别有效。
