Sun Dongguang, Li Quancheng, Tang Yuanzhang, Gong Weiyi, He Liangliang, Dou Zhi, Ni Jiaxiang
Department of Pain Management, Xuanwu Hospital, Capital Medical University, Beijing, China Department of Pain Management, the First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China.
Medicine (Baltimore). 2017 Nov;96(47):e8538. doi: 10.1097/MD.0000000000008538.
This study aimed to compare the effectiveness and safety of coblation annuloplasty and radiofrequency thermocoagulation for lumbar discogenic pain.Patients who suffered from lumbar discogenic pain and underwent coblation annuloplasty and radiofrequency thermocoagulation surgery were included. A questionnaire, including the visual analo scale (VAS), MacNab criteria, pain relief rate, and any complications due to surgery, was completed by the patients with the help of a trained volunteer who was blinded to the study. Data were collected at 1 week, and 1, 3, 6, and 12 months after surgery. Significant pain relief was defined as postoperative pain relief ≥50% compared with the preoperative state. Any complications during or after surgery were also recorded.A total of 122 patients were included; 37 patients were lost in the follow-up and 85 were evaluated. Among these, 45 patients underwent coblation annuloplasty (CA group, n = 45) and 40 underwent radiofrequency thermocoagulation procedures (RF group, n = 40).VAS pain scores were decreased at 1 week and 1, 3, 6, and 12 months postoperatively compared with preoperation in both groups (P < .05). The CA group had significantly lower VAS scores at 6 and 12 months of follow-up than did the RF group (P < .05). According to the modified MacNab criteria, the proportions of patients with excellent and/or good results at 3, 6, and 12 months of follow-up were significantly higher in the CA group compared with the RF group (P < .05).Only 2 patients reported soreness at the needle insertion site in the CA group. However, 3 patients had soreness at the needle insertion site, 3 had increased intensity of low back pain, 1 had intracranial hypotension, and 2 had new numbness in the leg and foot in the RF group. At the 1-year follow-up, this numbness was present all of the time. No major complications occurred in the CA group.Our study suggests that CA is a more effective and safe minimally invasive procedure than RF for treating lumbar discogenic pain.
本研究旨在比较低温等离子体环成形术与射频热凝术治疗腰椎间盘源性疼痛的有效性和安全性。纳入患有腰椎间盘源性疼痛并接受低温等离子体环成形术和射频热凝术手术的患者。患者在一名对研究不知情的经过培训的志愿者帮助下完成一份问卷,问卷包括视觉模拟量表(VAS)、MacNab标准、疼痛缓解率以及手术引起的任何并发症。在术后1周、1、3、6和12个月收集数据。显著疼痛缓解定义为与术前状态相比术后疼痛缓解≥50%。还记录手术期间或术后的任何并发症。
共纳入122例患者;37例患者失访,85例接受评估。其中,45例患者接受低温等离子体环成形术(CA组,n = 45),40例接受射频热凝术(RF组,n = 40)。
两组术后1周、1、3、6和12个月的VAS疼痛评分均较术前降低(P <.05)。CA组在随访6个月和12个月时的VAS评分显著低于RF组(P <.05)。根据改良的MacNab标准,CA组在随访3、6和12个月时优和/或良结果的患者比例显著高于RF组(P <.05)。
CA组仅2例患者报告针穿刺部位酸痛。然而,RF组有3例患者针穿刺部位酸痛,3例患者腰痛强度增加,1例患者颅内低压,2例患者腿部和足部出现新的麻木。在1年随访时,这种麻木一直存在。CA组未发生重大并发症。
我们的研究表明,对于治疗腰椎间盘源性疼痛,与射频热凝术相比,低温等离子体环成形术是一种更有效、更安全的微创手术。