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通过视频光度毛细管镜检查、荧光显微镜检查和激光多普勒血流仪对大鼠睾丸微循环进行研究。

Testicular microcirculation in the rat studied by videophotometric capillaroscopy, fluorescence microscopy and laser Doppler flowmetry.

作者信息

Damber J E, Bergh A, Fagrell B, Lindahl O, Rooth P

出版信息

Acta Physiol Scand. 1986 Mar;126(3):371-6. doi: 10.1111/j.1748-1716.1986.tb07829.x.

DOI:10.1111/j.1748-1716.1986.tb07829.x
PMID:2938420
Abstract

Testicular capillary blood flow was studied in rats using laser Doppler flowmetry, in vivo fluorescence microscopy and videophotometric capillaroscopy. All the methods revealed rhythmical oscillations in testicular microcirculation with a periodicity of 4-10 c.p.m. In arterioles, capillaries and small post-capillary vessels, periods of continuous blood flow alternated with periods of no or very low flow. No visible leakage of dextran-150 was observed from the testicular blood vessels. Four, 8 and 16 h after an s.c. injection of 200 IU hCG the blood flow was continuous and there was leakage of dextran-150 from the microvessels to the interstitial tissue. Twenty-four and 32 h after hCG the blood flow pattern was again rhythmical, and at 32 h there was no leakage of dextran-150. This suggests that hCG induces changes in blood flow and transvascular fluid exchange in the testis, perhaps by altering smooth muscle activity at the arteriolar-level.

摘要

采用激光多普勒血流仪、体内荧光显微镜和视频光度毛细血管镜研究了大鼠睾丸的毛细血管血流。所有方法均显示睾丸微循环存在节律性振荡,频率为4 - 10次/分钟。在小动脉、毛细血管和毛细血管后小血管中,持续血流期与无血流或极低血流期交替出现。未观察到睾丸血管中有可见的葡聚糖-150渗漏。皮下注射200 IU hCG后4、8和16小时,血流持续,有葡聚糖-150从微血管渗漏到间质组织。hCG注射后24和32小时,血流模式再次呈节律性,且在32小时时无葡聚糖-150渗漏。这表明hCG可能通过改变小动脉水平的平滑肌活动,诱导睾丸血流和跨血管液体交换发生变化。

相似文献

1
Testicular microcirculation in the rat studied by videophotometric capillaroscopy, fluorescence microscopy and laser Doppler flowmetry.通过视频光度毛细管镜检查、荧光显微镜检查和激光多普勒血流仪对大鼠睾丸微循环进行研究。
Acta Physiol Scand. 1986 Mar;126(3):371-6. doi: 10.1111/j.1748-1716.1986.tb07829.x.
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[Testicular microcirculation in rats measured with laser-Doppler flowmetry].[用激光多普勒血流仪测量大鼠睾丸微循环]
Actas Urol Esp. 1993 Mar;17(3):202-6.
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Relationship between human chorionic gonadotrophin-induced changes in testicular microcirculation and the formation of testicular interstitial fluid.人绒毛膜促性腺激素诱导的睾丸微循环变化与睾丸间质液形成之间的关系。
J Endocrinol. 1986 Jun;109(3):419-25. doi: 10.1677/joe.0.1090419.
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Rhythmical oscillations in rat testicular microcirculation as recorded by laser Doppler flowmetry.通过激光多普勒血流仪记录的大鼠睾丸微循环中的节律性振荡。
Acta Physiol Scand. 1983 Jun;118(2):117-23. doi: 10.1111/j.1748-1716.1983.tb07251.x.
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[Role of testosterone in the testicular microcirculatory changes produced in the rat by the administration of high doses of human chorionic gonadotrophin].
Arch Esp Urol. 1993 Oct;46(8):669-72.
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Treatment of rats with hCG induces inflammation-like changes in the testicular microcirculation.用促性腺激素释放激素(hCG)治疗大鼠会在睾丸微循环中引发类似炎症的变化。
J Reprod Fertil. 1987 Jan;79(1):135-43. doi: 10.1530/jrf.0.0790135.
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Testicular blood flow and microcirculation in rats after treatment with ethane dimethyl sulfonate.用乙烷二甲磺酸盐处理后大鼠的睾丸血流和微循环
Biol Reprod. 1987 Dec;37(5):1291-6. doi: 10.1095/biolreprod37.5.1291.
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Age-related differences in testicular microcirculation.睾丸微循环的年龄相关差异。
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HCG treatment increases intratesticular pressure in the abdominal testis of unilaterally cryptorchid rats.人绒毛膜促性腺激素治疗可增加单侧隐睾大鼠腹腔内睾丸的睾丸内压力。
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Localized expression of angiopoietin 1 and 2 may explain unique characteristics of the rat testicular microvasculature.血管生成素1和2的局部表达可能解释大鼠睾丸微血管系统的独特特征。
Biol Reprod. 2003 Oct;69(4):1231-7. doi: 10.1095/biolreprod.102.013375. Epub 2003 May 28.

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