Shub C, Cueto-Garcia L, Sheps S G, Ilstrup D M, Tajik A J
Am J Cardiol. 1986 Apr 15;57(11):971-5. doi: 10.1016/0002-9149(86)90741-1.
M-mode and 2-dimensional echocardiography were used to study 26 consecutive, unselected patients with pheochromocytoma over a 3-year period. Only 1 patient had congestive heart failure; more than half had no cardiac symptoms or abnormalities. The most common (80% of patients) echocardiographic pattern was normal left ventricular (LV) mass with normal or even increased systolic performance. When LV mass was increased, LV systolic function was either normal or only borderline depressed in most of the patients. Patients with echocardiographic LV hypertrophy had symmetric thickening of ventricular walls; no case of asymmetric septal hypertrophy was found. There was no correlation between 24-hour urinary norepinephrine excretion and any of the echocardiographic variables studied. In some patients, increased LV wall thicknesses did not correlate with increased LV mass as calculated by the Woythaler echocardiographic method. Left atrial enlargement was not seen in any patient, including those with increased LV mass. The electrocardiogram and echocardiogram may be discordant: Electrocardiographic LV hypertrophy was seen in 6 patients, of whom 5 had normal echocardiographic LV mass. In patients with pheochromocytoma who have no cardiac symptoms or other clinical evidence of cardiac involvement, echocardiographic findings are usually normal.
在3年时间里，使用M型和二维超声心动图对26例连续入选的嗜铬细胞瘤患者进行了研究。只有1例患者患有充血性心力衰竭；超过半数患者没有心脏症状或异常。最常见的超声心动图表现（80%的患者）是左心室（LV）质量正常，收缩功能正常甚至增强。当左心室质量增加时，大多数患者的左心室收缩功能正常或仅轻度降低。超声心动图显示左心室肥厚的患者心室壁呈对称性增厚；未发现非对称性室间隔肥厚病例。24小时尿去甲肾上腺素排泄量与所研究的任何超声心动图变量之间均无相关性。在一些患者中，左心室壁厚度增加与通过沃伊泰勒超声心动图方法计算的左心室质量增加并不相关。任何患者均未出现左心房扩大，包括左心室质量增加的患者。心电图和超声心动图可能不一致：6例患者出现心电图左心室肥厚，其中5例超声心动图显示左心室质量正常。在没有心脏症状或其他心脏受累临床证据的嗜铬细胞瘤患者中，超声心动图检查结果通常正常。
