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组织生长的大爆炸:顶端细胞缢缩转变成组织扩张。

The Big Bang of tissue growth: Apical cell constriction turns into tissue expansion.

机构信息

Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal

Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Porto, Portugal.

出版信息

J Cell Biol. 2018 Mar 5;217(3):807-808. doi: 10.1083/jcb.201801076. Epub 2018 Jan 31.

Abstract

How tissue growth is regulated during development and cancer is a fundamental question in biology. In this issue, Tsoumpekos et al. (2018. https://doi.org/10.1083/jcb.201705104) and Forest et al. (2018. https://doi.org/10.1083/jcb.201705107) identify Big bang (Bbg) as an important growth regulator of the wing imaginal disc.

摘要

组织在发育和癌症过程中是如何生长的,这是生物学中的一个基本问题。在本期中,Tsoumpekos 等人(2018. https://doi.org/10.1083/jcb.201705104)和 Forest 等人(2018. https://doi.org/10.1083/jcb.201705107)确定 Big bang (Bbg) 是 翅膀 imaginal 盘的一个重要生长调节剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccfb/5839798/bef937220f5f/JCB_201801076_Fig1.jpg

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