Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal
Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Porto, Portugal.
J Cell Biol. 2018 Mar 5;217(3):807-808. doi: 10.1083/jcb.201801076. Epub 2018 Jan 31.
How tissue growth is regulated during development and cancer is a fundamental question in biology. In this issue, Tsoumpekos et al. (2018. https://doi.org/10.1083/jcb.201705104) and Forest et al. (2018. https://doi.org/10.1083/jcb.201705107) identify Big bang (Bbg) as an important growth regulator of the wing imaginal disc.
组织在发育和癌症过程中是如何生长的,这是生物学中的一个基本问题。在本期中,Tsoumpekos 等人(2018. https://doi.org/10.1083/jcb.201705104)和 Forest 等人(2018. https://doi.org/10.1083/jcb.201705107)确定 Big bang (Bbg) 是 翅膀 imaginal 盘的一个重要生长调节剂。