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牛初乳在牙髓外科根尖周缺损中的应用：两例病例报告。

Use of bovine colostrum in periapical defects following surgical endodontics: Two case reports.

作者信息

Veeramachaneni Chandrasekhar, Gayathri Ch, Kakani Abhijeet K, Mohini R

机构信息

Department of Conservative Dentistry and Endodontics, Mamata Dental College, Khammam, India.

Department of Oral Pathology and Microbiology, Panineeya Mahavidyalaya Institute of Dental Sciences, Hyderabad, Telangana, India.

出版信息

J Conserv Dent. 2017 Sep-Oct;20(5):374-377. doi: 10.4103/JCD.JCD_411_15.

DOI:10.4103/JCD.JCD_411_15
PMID:29386790
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5767837/
Abstract

Periapical lesions are the most common pathological conditions involving teeth which often require surgical intervention. To achieve optimal healing both clinically and radiographically, bone grafts and barrier membranes have been used to fill the periapical defect after degranulation of the lesion. Colostrum is one of the new materials, which has osteoinductive or regenerative potential. The present case reports describe the use of bovine colostrum in the treatment of periapical inflammatory lesion with a follow-up period of 12 months. These case reports suggest that colostrum can be used to fill the periapical defect after degranulation, which has a favorable outcome.

摘要

根尖周病变是累及牙齿的最常见病理状况，通常需要手术干预。为了在临床和影像学上实现最佳愈合，在病变去肉芽后已使用骨移植和屏障膜来填充根尖周缺损。初乳是具有骨诱导或再生潜力的新材料之一。本病例报告描述了牛初乳在治疗根尖周炎性病变中的应用，随访期为12个月。这些病例报告表明，初乳可用于病变去肉芽后填充根尖周缺损，效果良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5265/5767837/c3b50441adb6/JCD-20-374-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5265/5767837/338953b799ed/JCD-20-374-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5265/5767837/c3b50441adb6/JCD-20-374-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5265/5767837/338953b799ed/JCD-20-374-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5265/5767837/c3b50441adb6/JCD-20-374-g002.jpg

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本文引用的文献

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J Endod. 2009 Jan;35(1):40-5. doi: 10.1016/j.joen.2008.10.002.
2
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J Endod. 2004 Nov;30(11):796-800. doi: 10.1097/01.don.0000136211.98434.66.
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Mechanisms of bone metastasis.骨转移的机制。
N Engl J Med. 2004 Apr 15;350(16):1655-64. doi: 10.1056/NEJMra030831.
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Bovine colostrums: a review of clinical uses.牛初乳：临床应用综述
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Apical periodontitis: a very prevalent problem.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002 Dec;94(6):651-2. doi: 10.1067/moe.2002.130322.
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Case selection for apical surgery: a retrospective evaluation of associated factors and rational.根尖手术的病例选择：相关因素及合理性的回顾性评估
J Endod. 2002 Jul;28(7):527-30. doi: 10.1097/00004770-200207000-00010.
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Oral findings in patients with primary Sjögren's syndrome and oral lichen planus--a preliminary study on the effects of bovine colostrum-containing oral hygiene products.原发性干燥综合征和口腔扁平苔藓患者的口腔检查结果——含牛初乳口腔卫生用品效果的初步研究
Clin Oral Investig. 2002 Mar;6(1):11-20. doi: 10.1007/s00784-001-0148-x.
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Effects of bovine immune and non-immune whey preparations on the composition and pH response of human dental plaque.牛免疫和非免疫乳清制剂对人牙菌斑成分及pH值反应的影响。
Eur J Oral Sci. 1999 Aug;107(4):244-50. doi: 10.1046/j.0909-8836.1999.eos107403.x.
9
Time-course and risk analyses of the development and healing of chronic apical periodontitis in man.人类慢性根尖周炎发展与愈合的时间进程及风险分析。
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Use of a bioresorbable guided tissue membrane at an adjunct to bony regeneration in cases requiring endodontic surgical intervention.
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