Olatoye Kazeem K, Arueya Gibson L
Department of Food Science and Technology College of Agriculture Kwara State University Malete Nigeria.
Department of Food Technology Faculty of Technology University of Ibadan Ibadan Nigeria.
Food Sci Nutr. 2017 Oct 25;6(1):94-100. doi: 10.1002/fsn3.533. eCollection 2018 Jan.
In this study, safety of novel food from aerial yam and , underutilized food materials with high-nutritive value and health benefits were investigated. Animal experiment involving the use of thirty (30) male albino rats was conducted for 28 days.Thereafter, rats in all groups were sacrificed and blood samples collected for biochemical analysis and hematological assay. Some vital organs were harvested and used for histological analysis. Biochemical and hematological parameters were not significantly ≤ .05 different among the treatment and controls. However there was an increase in monocytes, which is a reflection of immune boosting potential of the novel snack. No significant pathological changes were observed in liver and kidney of rats fed with this snack. Rats showed no signs of toxicity within the study period. These findings suggest that product may be safe and useful as an Immune adjuvant.
在本研究中，对来自薯蓣叶的新型食品以及具有高营养价值和健康益处的未充分利用的食品原料的安全性进行了调查。使用30只雄性白化大鼠进行了为期28天的动物实验。此后，处死所有组的大鼠并采集血样进行生化分析和血液学检测。摘取一些重要器官用于组织学分析。治疗组和对照组之间的生化和血液学参数差异不显著（≤0.05）。然而，单核细胞有所增加，这反映了这种新型零食的免疫增强潜力。喂食这种零食的大鼠肝脏和肾脏未观察到明显的病理变化。在研究期间，大鼠未表现出毒性迹象。这些发现表明该产品作为免疫佐剂可能是安全且有用的。
