Hashemi Mostafa, Dadgostar Ali Reza, Berjis Nezamoddin
Department of Otolaryngology, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Biomed Res. 2017 Dec 26;6:160. doi: 10.4103/abr.abr_171_15. eCollection 2017.
This study was carried out to compare mucociliary function (MCF) of nasal cavity before and after septorhinoplasty surgery by saccharin test.
This study was carried out on 70 patients who needed septorhinoplasty surgery in Kashani and Alzahra Hospital during 2013-2014 to measure MCF. Saccharin test was performed on the patients before surgery and on three more intervals 1 day, 1 week, and on month after ward and the readings were recorded. Saccharin test is performed by placing saccharin granules on the anterior part of inferior turbinate and the time the patient feels the sweet taste is recorded the normal range is below 30 min.
Mean of test for each time interval was obtained and comparison of measurements was made reading were mean of saccharin test before surgery (7.74 ± 1.65 min) the day after surgery (7.75 ± 1.7 min), on week after surgery (15.04 ± 3.4), and 1 month after surgery (8.49 ± 2.08 min). The readings before surgery did not have statistically significant difference with the readings 1 day after surgery = 0.99, but comparison of test results at other time intervals were significant ( < 0.001). A relative increase in saccharin test time was seen in a period of 1 month after surgery the rise was more noticeable in the 1 week compared to 1 month after surgery.
This study in the period after septorhinoplasty surgery MCF undergoes slight impairment that gradually progresses to normal values during 1 month after surgery.
本研究旨在通过糖精试验比较鼻中隔成形术后鼻腔的黏液纤毛功能(MCF)。
本研究对2013 - 2014年期间在卡沙尼医院和阿尔扎赫拉医院需要进行鼻中隔成形术的70例患者进行MCF测量。在手术前、术后1天、1周和1个月这三个时间点对患者进行糖精试验,并记录读数。糖精试验通过将糖精颗粒放置在下鼻甲前部进行,记录患者感觉到甜味的时间,正常范围低于30分钟。
获得每个时间间隔的测试平均值,并对测量结果进行比较。读数分别为术前糖精试验平均值(7.74 ± 1.65分钟)、术后1天(7.75 ± 1.7分钟)、术后1周(15.04 ± 3.4)和术后1个月(8.49 ± 2.08分钟)。术前读数与术后1天读数无统计学显著差异(P = 0.99),但其他时间间隔的测试结果比较有显著差异(P < 0.001)。术后1个月内糖精试验时间相对增加,术后1周的上升比术后1个月更明显。
本研究表明鼻中隔成形术后一段时间内MCF会有轻微损害,术后1个月内逐渐恢复至正常水平。