R Chethana, Mishra Prasun, Dixit Shivani, Raghavan Rakhee, Deepika S S Pranaya
Department of Otorhinolaryngology, Bharati Vidyapeeth Medical College Pune, Maharashtra Pune, India.
Indian J Otolaryngol Head Neck Surg. 2023 Dec;75(4):2990-2992. doi: 10.1007/s12070-023-03915-x. Epub 2023 Jun 2.
Nasal mucociliary clearance (NMC) plays an important role in removal of inhaled particles. The aim of this study was to assess the normal nasal mucociliary clearance time in Indian adult population in age group 18-60 years. A cross sectional, descriptive, observational study was performed. Two hundred participants in the age group 18-60 years were included in this study. Saccharin transit test was performed in these subjects. Saccharin particle was placed 0.5 cm away from the inferior turbinate from its anterior part. The participants were asked to inform the appearance of sweet taste. Duration between placement of particle and the appearance of taste was noted in minutes. Mean saccharin transit time was 9.44?2.73 minutes. There was no statistically significant difference in saccharin transit time between males & females. Nasal mucociliary clearance time between < 40 years & ≥40 years was compared and there was no significant difference between the 2 groups. The normal mucociliary clearance value in healthy adult Indian population-based on saccharin transit time is 9.44 ± 2.73 min. The earliest change in respiratory defense mechanism is change in nasal mucociliary clearance time and saccharin test is a simple, easy test to detect this.
The online version contains supplementary material available at 10.1007/s12070-023-03915-x.
鼻黏液纤毛清除功能（NMC）在清除吸入颗粒方面起着重要作用。本研究的目的是评估18 - 60岁印度成年人群的正常鼻黏液纤毛清除时间。进行了一项横断面、描述性、观察性研究。本研究纳入了200名年龄在18 - 60岁的参与者。对这些受试者进行了糖精转运试验。将糖精颗粒放置在下鼻甲前部前方0.5厘米处。要求参与者告知甜味出现的情况。记录颗粒放置与味道出现之间的持续时间（以分钟为单位）。平均糖精转运时间为9.44±2.73分钟。男性和女性之间的糖精转运时间在统计学上没有显著差异。比较了<40岁和≥40岁组之间的鼻黏液纤毛清除时间，两组之间没有显著差异。基于糖精转运时间，健康成年印度人群的正常黏液纤毛清除值为9.44±2.73分钟。呼吸防御机制最早的变化是鼻黏液纤毛清除时间的变化，糖精试验是检测这一变化的简单易行的试验。
在线版本包含可在10.1007/s12070 - 023 - 03915 - x获取的补充材料。
