Ames Jeff, Al-Samaraee Ahmad, Takahashi Takashi
Department of Radiology, University of Minnesota, Minneapolis, MN, USA.
Musculoskeletal Division, Department of Radiology, University of Minnesota, Minneapolis, MN, USA.
Case Rep Radiol. 2017;2017:9159035. doi: 10.1155/2017/9159035. Epub 2017 Dec 17.
A rare presentation of extramedullary multiple myeloma in the soft tissues of the bilateral thighs prompted a literature review of published cases of extramedullary multiple myeloma (EM-MM) and solitary plasmacytomas to determine the relative anatomic distribution of these lesions. All available published cases in English were included in the analysis, dating back to 1966 and including 2,538 extramedullary myeloma or solitary plasmacytoma lesions. Analysis of the anatomic location of EM-MM lesions demonstrates the majority being in the upper airway (33.8%), soft tissues including retroperitoneum and abdomen (14.1%), gastrointestinal tract (10.3%), central nervous system, head and neck (16.0%), and GU (2.4%). We were able to find only 44 documented cases of extremity soft tissue lesions, comprising 1.7% of all lesions.
双侧大腿软组织出现罕见的髓外多发性骨髓瘤，促使我们对已发表的髓外多发性骨髓瘤（EM-MM）和孤立性浆细胞瘤病例进行文献回顾，以确定这些病变的相对解剖分布。分析纳入了所有可用的英文已发表病例，时间可追溯到1966年，包括2538例髓外骨髓瘤或孤立性浆细胞瘤病变。对EM-MM病变的解剖位置分析表明，大多数病变位于上呼吸道（33.8%）、包括腹膜后和腹部的软组织（14.1%）、胃肠道（10.3%）、中枢神经系统、头颈部（16.0%）和泌尿生殖系统（2.4%）。我们仅发现44例记录在案的肢体软组织病变病例，占所有病变的1.7%。
