Calogero Aldo E, Burgio Giovanni, Condorelli Rosita A, Cannarella Rossella, La Vignera Sandro
a Department of Clinical and Experimental Medicine , University of Catania , Catania , Italy.
Aging Male. 2019 Mar;22(1):12-19. doi: 10.1080/13685538.2018.1434772. Epub 2018 Feb 2.
Benign prostatic hyperplasia (BPH) is very common in aging men and causes lower urinary tract symptoms (LUTS), which decrease health-related quality of life. A number of evidence suggests that other than ageing, modifiable factors, such as increasing prostate volume, obesity, diet, dyslipidemia, hormonal imbalance, hypertension, metabolic syndrome, alcohol, and smoking, also contribute to the development of BPH and/or LUTS. More recently, erectile dysfunction (ED) has been linked to LUTS/BPH as a part of this syndrome, suggesting that patients with BPH or LUTS easily develop ED, and that LUTS/BPH symptoms often coexist with ED. This article focuses on the epidemiology and risk factors of the combined phenotype LUTS/BPH - ED.
良性前列腺增生(BPH)在老年男性中非常常见,会导致下尿路症状(LUTS),进而降低与健康相关的生活质量。大量证据表明,除衰老外,可改变的因素,如前列腺体积增大、肥胖、饮食、血脂异常、激素失衡、高血压、代谢综合征、酒精和吸烟等,也会促使BPH和/或LUTS的发生。最近,勃起功能障碍(ED)作为该综合征的一部分与LUTS/BPH相关联,这表明BPH或LUTS患者很容易出现ED,且LUTS/BPH症状常与ED并存。本文重点关注LUTS/BPH - ED联合表型的流行病学及危险因素。