School of Biological and Medical Engineering, Hefei University of Technology, Hefei, China.
School of Food Science and Engineering, Hefei University of Technology, Hefei, China.
J Antibiot (Tokyo). 2018 Mar;71(4):477-479. doi: 10.1038/s41429-017-0021-z. Epub 2018 Feb 5.
A new macrolactam derivative, designated as nivelactam B (1), was isolated from the fermentation broth of marine-derived actinomycete HF-11225. Its structure was determined on the basis of spectroscopic analysis, including 1D and 2D NMR techniques, as well as ESI-MS and comparison with data from the literature. Compound 1 showed weak cytotoxic and antifungal activities.
一种新的大环内酯衍生物，命名为 nive l actam B（1），从海洋来源放线菌 HF-11225 的发酵液中分离得到。其结构是通过包括 1D 和 2D NMR 技术以及 ESI-MS 在内的光谱分析，并与文献数据进行比较来确定的。化合物 1 表现出较弱的细胞毒性和抗真菌活性。
