Wong Sze H, Turbin Roger E, Frohman Larry P
Institute of Ophthalmology & Visual Science, Rutgers New Jersey Medical School, Newark.
Digit J Ophthalmol. 2017 Oct 28;23(4):13-14. doi: 10.5693/djo.02.2017.09.002. eCollection 2017.
We report the case of a 66-year-old man with Takayasu arteritis who developed photic and postprandial amaurosis occurring at a corticosteroid dose <40 mg per day, despite concurrent methotrexate. The amaurosis resolved with correction of anemia by packed red blood cell transfusion. Marginal retinal perfusion in Takayasu arteritis may precipitate symptomatic hypoxia as a result of eating a meal or exposing the eye to bright lights. Correction of anemia improves oxygen delivery to the hypoxic retina and relieves recurrent amaurosis.
我们报告了一例66岁患有高安动脉炎的男性患者,尽管同时使用了甲氨蝶呤,但在皮质类固醇剂量<40mg/天时仍出现了光性和餐后黑矇。通过输注浓缩红细胞纠正贫血后,黑矇症状得到缓解。高安动脉炎患者视网膜边缘灌注可能因进食或眼睛暴露于强光而引发症状性缺氧。纠正贫血可改善向缺氧视网膜的氧气输送,并缓解复发性黑矇。