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幼儿的视网膜血管异常:诊断难题。

Abnormal Retinal Vasculature in a Young Child: A Diagnostic Dilemma.

机构信息

Department of Vitreo-Retinal Services, Aravind Eye Hospital, Madurai, Tamil Nadu, India.

出版信息

Ocul Immunol Inflamm. 2021 Jan 2;29(1):175-178. doi: 10.1080/09273948.2019.1672199. Epub 2019 Oct 31.

DOI:10.1080/09273948.2019.1672199
PMID:31671013
Abstract

: To report the case of a young child who presented with sudden visual loss and characteristic abnormal retinal vasculature.: Case Report: A 13-year-old Indian boy presented with sudden visual loss in the left eye (20/1200) for 1 month, associated with recent-onset of seizures. Ocular examination showed a relative afferent pupillary defect, neovascularization of iris, absence of retinal vasculature beyond second branching, and arterio-venous shunts at the junction of vascular and avascular retina. Fundus fluorescein angiography showed delayed arm-to-retina time, leading edge of fluorescein dye in arteries and peripheral capillary non-perfusion areas.Peripheral pulses were absent and carotid doppler showed bilateral carotid artery occlusion (left one being worse affected), suggestive of Takayasu's arteritis (TA). Despite being started on immunotherapy, he lost complete vision in the left eye.: TA may present initially to ophthalmologists, who need to maintain a high index of suspicion for early diagnosis and management of this life-threatening disease.

摘要

报告一例儿童病例,其表现为突发性视力丧失和特征性异常视网膜血管。

病例报告

一名 13 岁印度男孩左眼突然失明(20/1200)1 个月,伴有近期发作的癫痫。眼部检查显示相对传入性瞳孔缺陷、虹膜新生血管形成、视网膜第二分支以外的血管缺失以及血管和无血管视网膜交界处的动静脉分流。眼底荧光血管造影显示臂-视网膜时间延迟,动脉内荧光素染料前缘和周边毛细血管无灌注区。周围脉搏消失,颈动脉多普勒显示双侧颈动脉闭塞(左侧更严重),提示 Takayasu 动脉炎(TA)。尽管他开始接受免疫治疗,但左眼完全失明。

TA 可能最初表现为眼科医生,他们需要保持高度怀疑,以便早期诊断和管理这种危及生命的疾病。

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引用本文的文献

1
Posterior segment manifestations of Takayasu arteritis: A narrative review.Takayasu 动脉炎的后节段表现:叙述性综述。
Indian J Ophthalmol. 2024 May 1;72(5):637-647. doi: 10.4103/IJO.IJO_1346_23. Epub 2024 Apr 22.
2
Ocular Manifestations of Takayasu's Arteritis-A Case-Based Systematic Review and Meta-Analysis.高安动脉炎的眼部表现——基于病例的系统评价与荟萃分析
J Clin Med. 2023 May 29;12(11):3745. doi: 10.3390/jcm12113745.
3
Therapeutic Management of Ocular Ischemia in Takayasu's Arteritis: A Case-Based Systematic Review.
Takayasu 动脉炎致眼部缺血的治疗管理:基于病例的系统评价。
Front Immunol. 2022 Jan 14;12:791278. doi: 10.3389/fimmu.2021.791278. eCollection 2021.
4
Takayasu Arteritis Presenting as Bilateral Ocular Ischemic Syndrome.以双侧眼部缺血综合征为表现的高安动脉炎
Vasc Specialist Int. 2020 Sep 30;36(3):163-169. doi: 10.5758/vsi.200031.